52092-12-3 Usage
Description
(16β)-16-Methyl-17,21-bis(1-oxopropoxy)pregna-1,4,9(11)-triene-3,20-dione, also known as Beclomethasone Dipropionate EP Impurity I, is a chemical compound derived from the glucocorticoid class. It is an impurity found in Beclomethasone (B131000), which is a medication used for various respiratory and inflammatory conditions.
Uses
Used in Pharmaceutical Industry:
(16β)-16-Methyl-17,21-bis(1-oxopropoxy)pregna-1,4,9(11)-triene-3,20-dione is used as an impurity in the production of Beclomethasone, a glucocorticoid medication. Its presence is significant for the development and formulation of Beclomethasone, which is utilized for the treatment of chronic asthma and allergic rhinitis.
Used in Respiratory Applications:
(16β)-16-Methyl-17,21-bis(1-oxopropoxy)pregna-1,4,9(11)-triene-3,20-dione contributes to the antiallergic and antiasthmatic properties of Beclomethasone when used as an inhalant. This application aids in the management of chronic asthma symptoms and allergic reactions.
Used in Topical Inflammatory Treatments:
In addition to its role in respiratory treatments, (16β)-16-Methyl-17,21-bis(1-oxopropoxy)pregna-1,4,9(11)-triene-3,20-dione also plays a part in the anti-inflammatory effects of Beclomethasone when applied topically. This application is beneficial for treating various skin conditions and inflammations.
Check Digit Verification of cas no
The CAS Registry Mumber 52092-12-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,0,9 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 52092-12:
(7*5)+(6*2)+(5*0)+(4*9)+(3*2)+(2*1)+(1*2)=93
93 % 10 = 3
So 52092-12-3 is a valid CAS Registry Number.
52092-12-3Relevant articles and documents
9β,11β-Epoxy-5β-corticoids
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, (2008/06/13)
17α-Acyloxy-5α-pregnanes (I) and 17α-acyloxy-5α-pregnanes (IV) have an excellent activity split providing high topical anti-inflammatory activity with very low systemic side effects.
