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521-35-7

521-35-7

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521-35-7 Usage

Chemical Properties

thin platelets

Uses

A metabolite of Tetrahydrocannabinol (T293200). A psychoactive substance cannabinoid that acts as a weak agonist of the CB1 and CB2 receptors.

Reactivity Profile

CANNABINOL is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Fire Hazard

Flash point data for CANNABINOL are not available, but CANNABINOL is probably combustible.

Biological Activity

CB 1 and CB 1 receptor agonist (K i values are 126 and 211 nM respectively). Inhibits adenylyl cyclase (EC 50 values are 120 and 261 nM for CB 1 and CB 2 receptors respectively) and suppresses immune cell function. Major constituent of cannabis; displays little or no psychotropic activity.

Purification Methods

Cannabinol crystallises from pet ether and sublimes in a vacuum. [Meitzer et al. Synthesis 985 1981, Beilstein 17 II 151, 17 III/IV 1652.]

Check Digit Verification of cas no

The CAS Registry Mumber 521-35-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 521-35:
(5*5)+(4*2)+(3*1)+(2*3)+(1*5)=47
47 % 10 = 7
So 521-35-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H26O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9-13,22H,5-8H2,1-4H3

521-35-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 6,6,9-trimethyl-3-pentylbenzo[c]chromen-1-ol

1.2 Other means of identification

Product number -
Other names cannabinol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:521-35-7 SDS

521-35-7Downstream Products

521-35-7Relevant articles and documents

Iodine-Promoted Aromatization of p -Menthane-Type Phytocannabinoids

Pollastro, Federica,Caprioglio, Diego,Marotta, Patrizia,Moriello, Aniello Schiano,De Petrocellis, Luciano,Taglialatela-Scafati, Orazio,Appendino, Giovanni

, p. 630 - 633 (2018)

Treatment with iodine cleanly converts various p-menthane-type phytocannabinoids and their carboxylated precursors into cannabinol (CBN, 1a). The reaction is superior to previously reported protocols in terms of simplicity and substrate range, which inclu

METHODS FOR SELECTIVE AROMATIZATION OF CANNABINOIDS

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Paragraph 0044-0049; 0053-0054; 0067-0069, (2022/02/11)

The present invention relates to methods of selective aromatization of cannabinoids. Such methods may be used, among other purposes, for the removal of delta-9-tetrahydrocannabinol from hemp extracts or other samples by selectively converting delta-9-tetrahydrocannabinol to cannabinol using ortho-quinone catalysts.

APPARATUS FOR CANNABINOL GENERATION AND METHODS OF USING THE SAME

-

, (2021/12/17)

The present disclosure methods for producing cannabinol from Cannabis compositions. The present disclosure further provides apparatuses for the production of cannabinol from Cannabis compositions.

METHODS FOR CONVERTING TETRAHYDROCANNABINOLIC ACID INTO CANNABINOLIC ACID

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Paragraph 0049, (2021/03/05)

Disclosed herein is a method for converting tetrahydrocannabinolic acid (THCA) to cannabinolic acid (CBNA). The method comprises contacting an input material comprising THCA with a benzoquinone reagent under reaction conditions comprising: (i) a reaction temperature that is within a target reaction-temperature range; and (ii) a reaction time that is within a target reaction-time range, to provide an output material in which at least a portion of the THCA from the input material has been converted into CBNA.