11alpha-Hydroxyestrone is a naturally occurring metabolite of the hormone estrone, which is a form of estrogen. It is produced in the body through the action of the enzyme 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which converts estrone into 11alpha-hydroxyestrone. 11alpha-Hydroxyestrone has been studied for its potential role in various physiological processes, including bone metabolism and the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Research suggests that 11alpha-hydroxyestrone may have different effects compared to other estrogen metabolites, potentially influencing health outcomes such as bone density and stress response. However, the exact mechanisms and implications of 11alpha-hydroxyestrone in human health are still being investigated, and more research is needed to fully understand its role and potential therapeutic applications.
5210-15-1
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Basic information
- Product Name: 11alpha-Hydroxyestrone
- Synonyms:
- CAS NO:5210-15-1
- Molecular Formula:
- Molecular Weight: 286.371
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 11alpha-Hydroxyestrone(CAS DataBase Reference)
- NIST Chemistry Reference: 11alpha-Hydroxyestrone(5210-15-1)
- EPA Substance Registry System: 11alpha-Hydroxyestrone(5210-15-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 5210-15-1(Hazardous Substances Data)
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Definition
11alpha-Hydroxyestrone is a naturally occurring estrogen metabolite.Role
It plays a role in the regulation of the menstrual cycle and other reproductive processes.Derivation
It is derived from estrone, a major estrogen in women.Production
It is primarily produced in the liver and kidneys.Cancer Link
11alpha-Hydroxyestrone has been linked to certain cancers, including breast and endometrial cancer.Biomarker Potential
It has been studied for its potential as a biomarker for these diseases.Therapeutic Applications
It has been explored for its potential therapeutic applications in hormone replacement therapy and the treatment of estrogen-related disorders.Clinical Significance
11alpha-Hydroxyestrone is an important hormone with diverse biological functions and potential clinical significance.Check Digit Verification of cas no
The CAS Registry Mumber 5210-15-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,1 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.Calculate Digit Verification of CAS Registry Number 5210-15:
(6*5)+(5*2)+(4*1)+(3*0)+(2*1)+(1*5)=51
51 % 10 = 1
So 5210-15-1 is a valid CAS Registry Number.
5210-15-1Upstream product
5210-15-1Downstream Products
- 95230-29-8 methyl (3-benzyloxy-17-oxoestra-1,3,5(10)trien-11α-yl 2,3,4-tri-O-acetyl-β-D-glucopyranosid)uronate
- 95230-30-1 methyl (3-benzyloxy-17β-hydroxyestra-1,3,5(10)trien-11α-yl 2,3,4-tri-O-acetyl-β-D-glucopyranosid)uronate
- 52057-95-1 3,17β-dihydroxyestra-1,3,5(10)trien-11α-yl hydrogen succinate
- 1464-61-5 11alpha-Hydroxyestradiol
- 92115-44-1 3,11α-dihydroxyestra-1,3,5(10)trien-17-one 3-benzyl ether
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11alpha-Hydroxyestrone
