52120-75-9

Basic information

• Product Name: 1-(1-phenyl-ethylamino)-3-thiazol-2-yloxy-propan-2-ol
• CAS NO: 52120-75-9
• Molecular Weight: 278.375
• Mol File: 52120-75-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(1-phenyl-ethylamino)-3-thiazol-2-yloxy-propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-phenyl-ethylamino)-3-thiazol-2-yloxy-propan-2-ol(52120-75-9)
• EPA Substance Registry System: 1-(1-phenyl-ethylamino)-3-thiazol-2-yloxy-propan-2-ol(52120-75-9)

Safety Data

• Hazardous Substances Data: 52120-75-9(Hazardous Substances Data)

Upstream product

• 39832-47-8 1-(thiazol-2-yloxy)-2,3-epoxypropane 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 39832-49-0 2-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-thiazole 
• 39832-45-6 3-thiazol-2-yloxy-propane-1,2-diol 

Relevant articles and documents

THIAZOLE CARDIOVASCULAR AGENTS

1-Amino-3-2-thiazoloxy!-2-propanol and substituted 1-amino derivatives thereof; 3-2-thiazoloxy!-1,2-epoxypropane 5-thiazol-2-oxymethylene!-oxazolidine and/or N-substituted and/or 2-substituted oxazolidine, derivatives thereof and methods of preparing such compounds. The above 1-amino-3-2-thiazoloxy!-2-propanol and derivatives exhibit . beta.-adrenergic stimulating cardiovascular activity and are useful for the treatment of abnormal heart conditions in mammals. The above 3-2-thiazoloxy!-1,2-epoxypropane and derivatives are useful as intermediates for the aforementioned cardiovascular agents. The 5-thiazol-2-oxymethylene!-oxazolidine and derivatives are intermediates for aforementioned cardiovascular agents. The 1-amino-3-2-thiazoloxy!-2-propanol and derivatives can be prepared by base or acid hydrolysis of the corresponding 5-thiazol-2-oxymethylene!-oxazolidine or derivatives; or by treatment of the corresponding 3-2-thiazoloxy!-2,3-epoxypropane or derivative with the desired amine or amino-derivative.