52121-59-2Relevant academic research and scientific papers
Synthesis and biological evaluation of novel pyrazoline derivatives as anti-inflammatory and antioxidant agents
Khalil, Nadia A.,Ahmed, Eman M.,El-Nassan, Hala B.,Ahmed, Osama K.,Al-Abd, Ahmed M.
body text, p. 995 - 1002 (2012/10/08)
A series of novel 5-aryl-3-cyclopropyl-4,5-dihydropyrazole derivatives 2a-p were synthesized via cyclization of chalcones 1a-h with thiosemicarbazide or semicarbazide HCl and evaluated as anti-inflammatory/antioxidant agents. The structures were confirmed
PYRIDINE ANCHORS FOR HMG-COA REDUCTASE INHIBITORS
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, (2008/06/13)
Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have a quinoline or a pyridine anchor attached by means of a linker to a binding domain sidechain, which compounds inhibit the e
Phosphorus-Containing Inhibitors of HMG-CoA Reductase. 2. Synthesis and Biological Activites of a Series of Substituted Pyrydynes Containing a Hydroxyphosphinyl Moiety
Robl, Jeffrey A.,Duncan, Laurelee A.,Pluscec, Jelka,Karanevsky, Donald S.,Gordon, Eric M.,et al.
, p. 2804 - 2815 (2007/10/02)
A series of 2,3,4,(5),6-substituted pyridines containing a hydroxyphosphinyl functionality have been prepared and were evaluated for their ability to inhibit the enzyme HMG-CoA reductase.Systematic substitution of both R1-R4 and X-Y
Dialkylaminophenylethyl (or vinyl) cyclopropyl carbinols
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, (2008/06/13)
Aryl substituted diketones and keto-esters, useful as antiviral agents and insecticides, are prepared by reacting an arylalkyl or arylalkenyl iodide with a metal salt of the appropriate diketone or keto-ester. The intermediate iodides are prepared by cond
Aryl substituted diketones
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, (2008/06/13)
Aryl substituted diketones and keto-esters, useful as antiviral agents and insecticides, are prepared by reacting an arylalkyl or arylalkenyl iodide with a metal salt of the appropriate diketone or keto-ester.
