52121-97-8

Upstream product

• 52121-86-5 6-(4-methoxyphenyl)-3-hexenyl bromide 
• 57840-61-6 6-bromo-1-(4-methoxyphenyl)-1-hexanone 
• 768-60-5 4-methoxyphenylacetylen 
• 1398415-49-0 1-(6-iodohex-1-yn-1-yl)-4-methoxybenzene 
• 23464-45-1 6-(4-methoxyphenyl)-hexyl bromide 

Downstream Products

• 52122-53-9 7-(4-methoxyphenyl)heptyl phenyl sulfide 
• 52122-32-4 4-[6-(4-methoxyphenyl)hexyl]-3,5-heptanedione 

Relevant academic research and scientific papers

Palladium-catalyzed alkyne insertion/Suzuki reaction of alkyl iodides

A palladium-catalyzed alkyne insertion/Suzuki reaction with unactivated alkyl iodides is described. Under the reaction conditions, selective migratory insertion of alkynes avoids β-hydride elimination and provides a facile synthesis of stereodefined, tetrasubstituted olefins. The transformation offers broad substrate scope for both the alkyl iodide and boron nucleophile. Mechanistic studies have revealed inversion of the stereocenter for the carbon bearing the iodide.

Aryl substituted diketones

Aryl substituted diketones and keto-esters, useful as antiviral agents and insecticides, are prepared by reacting an arylalkyl or arylalkenyl iodide with a metal salt of the appropriate diketone or keto-ester.

Methylenedioxyphenyl substituted aliphatic diketones

Aryl substituted diketones and keto-esters, useful as antiviral agents and insecticides, are prepared by reacting an arylalkyl or arylalkenyl iodide with a metal salt of the appropriate diketone or keto-ester.

Aryl substituted ketones

Aryl substituted tertiary carbinols, useful as antiviral agents and insecticides, are prepared by reacting the Grignard reagent derived from an arylalkyl or arylalkenyl iodide with a dialkyl ketone or an alkyl alkenyl ketone; or by reacting an arylalkyl or arylalkenyl ketone with an alkyl- or alkenylmagnesium halide.