52123-65-6

Basic information

• Product Name: (Z)-2-isopropyl-1-phenyldiazene 1-oxide
• CAS NO: 52123-65-6
• Molecular Weight: 164.207
• Mol File: 52123-65-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (Z)-2-isopropyl-1-phenyldiazene 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-isopropyl-1-phenyldiazene 1-oxide(52123-65-6)
• EPA Substance Registry System: (Z)-2-isopropyl-1-phenyldiazene 1-oxide(52123-65-6)

Safety Data

• Hazardous Substances Data: 52123-65-6(Hazardous Substances Data)

Upstream product

• 135-20-6 cupferron 
• 920-39-8 isopropylmagnesium bromide 
• 16046-28-9 N'-p-Toluolsulfonyloxy-N-phenyl-diimid-N-oxid 
• 16046-28-9 N-Phenyl-N'-tosyloxydiimid-N-oxid 
• 77613-41-3 C₄H₁₀N₂O₂ 
• 10218-84-5 N,N-dichloroisopropylamine 
• 586-96-9 Nitrosobenzene 
• 98-95-3 nitrobenzene 
• 75-31-0 isopropylamine 

Downstream Products

• 139215-28-4 2-isopropyl-3-phenyl-2H-indazole 

Relevant articles and documents

Rh(III)-Catalyzed Regio- and Chemoselective [4 + 1]-Annulation of Azoxy Compounds with Diazoesters for the Synthesis of 2H-Indazoles: Roles of the Azoxy Oxygen Atom

A Rh(III)-catalyzed tandem C-H alkylation/intramolecular decarboxylative cyclization of azoxy compounds with diazoesters for the synthesis of 3-acyl-2H-indazoles is disclosed. The azoxy instead of the azo group enables a distinct approach for cyclative capture, leading to a [4 + 1]-annulation rather than a classic [4 + 2] manner. The azoxy oxygen atom is traceless after annulation, and further removal from the product is not required. This reaction features a complete regioselectivity for unsymmetrical azoxybenzenes and a compatibility of monoaryldiazene oxides.

N-LITHIUM DERIVATIVES OF ALIPHATIC AMINES IN THE SYNTHESIS OF 1-ALKYL-2-PHENYLDIAZENE 2-OXIDES

Magnesium derivatives of aliphatic amines containing α-hydrogen atoms, in contrast to t-BuNHMgBr, do not form phenylaliphatic diazene oxides upon reaction with nitrobenzene, but rather reduce it to azobenzene and azoxybenzene.Asymmetric diazene oxides are formed when the magnesium derivatives are replaced by lithium derivatives.The reaction of t-BuNHLi with dimethylnitramine gives 1,3,5-trimethyl-1,3,5-triazacyclohexane.