521301-93-9 Usage
1H-Imidazo[1,5-a]indol-1-one, 2-ethyl-2,3-dihydro-3-thioxo-(9CI) properties and specific content
A chemical compound consisting of 12 carbon atoms, 11 hydrogen atoms, 1 nitrogen atom, 1 oxygen atom, and 1 sulfur atom.
2. Heterocyclic compound
A compound containing a ring structure with atoms of different elements, such as carbon, nitrogen, and sulfur, in the ring.
3. Imidazole and indole rings fusion
The compound has an imidazole ring connected to an indole ring, forming a unique structure with potential biological activities.
4. Thioxo group attachment
A thioxo group (a sulfur-oxygen double bond) is attached to the third carbon of the ethyl side chain, which may contribute to its potential applications.
5. Potential pharmaceutical applications
The compound is being researched for its possible biological activities, such as
a. Anti-inflammatory properties
Reducing inflammation in the body.
b. Antimicrobial properties
Inhibiting the growth of microorganisms, such as bacteria and fungi.
c. Anticancer properties
Inhibiting the growth and spread of cancer cells.
6. Potential industrial applications
The compound may be useful in the synthesis of other organic compounds due to its unique heterocyclic structure.
7. Need for further research and testing
To determine the full range of potential uses and effects of 1H-Imidazo[1,5-a]indol-1-one, 2-ethyl-2,3-dihydro-3-thioxo-(9CI), more research and testing are necessary.
Check Digit Verification of cas no
The CAS Registry Mumber 521301-93-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,2,1,3,0 and 1 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 521301-93:
(8*5)+(7*2)+(6*1)+(5*3)+(4*0)+(3*1)+(2*9)+(1*3)=99
99 % 10 = 9
So 521301-93-9 is a valid CAS Registry Number.
521301-93-9Relevant academic research and scientific papers
Novel synthesis of bicycles with fused pyrrole, indole, oxazole, and imidazole rings
Katritzky, Alan R.,Singh, Sanjay K.,Bobrov, Sergey
, p. 9313 - 9315 (2007/10/03)
Reactions of benzotriazol-1-yl(1H-pyrrol-2-yl)methanone 10 and benzotriazol-1-yl(1H-indol-2-yl)methanone 11 with diverse ketones, isocyanates, and isothiocyanates in the presence of base afforded pyrrolo[1,2-c]oxazol-1-ones 1, oxazolo[3,4-a]indol-1-ones 2, pyrrolo[1,2-c]imidazoles 3, and imidazo[1,5-a]indoles 4 by a simple one-step procedure.
Both 5-arylidene-2-thioxodihydropyrimidine-4,6(1H,5H)-diones and 3-thioxo-2,3-dihydro-1H-imidazo[1,5-a]indol-1-ones are light-dependent tumor necrosis factor-α antagonists
Voss, Matthew E.,Carter, Percy H.,Tebben, Andrew J.,Scherle, Peggy A.,Brown, Gregory D.,Thompson, Lorin A.,Xu, Meizhong,Lo, Yvonne C.,Yang, Gengjie,Liu, Rui-Qin,Strzemienski, Paul,Everlof, J. Gerry,Trzaskos, James M.,Decicco, Carl P.
, p. 533 - 538 (2007/10/03)
Based on the realization that N-alkyl 5-arylidene-2-thioxo-1,3-thiazolidin-4-ones are tumor necrosis factor-α antagonists, we discovered two additional classes of antagonists: 3-thioxo-2,3-dihydro-1H-imidazo[1,5-a]indol-1-ones (via rational design) and 5-arylidene-2-thioxodihydropyrimidine-4,6(1H,5H)-diones (via computer-guided screening). Chemical modification of the lead structures showed that the structure-activity relationship profiles for both of these series were dependent on the electronic properties of the molecules. Subsequent studies showed that they were light-dependent inhibitors.
