521310-13-4

Upstream product

• 280142-38-3 (4R,5R)-N,N'-bis[(1S)-1-phenylethyl]-3,6-divinyl-1,7-octadiene-4,5-diamine 
• 880517-61-3 (4R,5R)-1,3-bis[(1S)-1-phenylethyl]-4,5-bis(1-vinylprop-2-en-1-yl)-1,3,2-diazaphospholidine 2-oxide 
• 880517-67-9 (3aR,4R,7S,7aR)-1,3-Bis-((S)-1-phenyl-ethyl)-4,7-divinyl-1,3,3a,4,7,7a-hexahydro-benzo[1,3,2]diazaphosphole 2-oxide 
• 521310-11-2 N,N'-bis[((S)-1-phenylethyl)]-4(R),5(R)-di(1-ethenyl-2-propenyl)imidazolidine 

Relevant academic research and scientific papers

Stereoselective synthesis of 3,6-disubstituted 1,2-diaminocyclohexanes through ring-closing metathesis of 4,5-diamino-1,7-octadiene derivatives

3,6-Disubstituted 4,5-di[(S)-1-phenylethylamino]-1,7-octadienes with different configurations at the carbon stereocenters were protected as dihydrochlorides or cyclic phosphorous diamides and then converted into (1R,2R)-3,6-disubstituted 1,2-diaminocycloh

Progress towards the Stereoselective Synthesis of 3,6-Disubstituted 1,2-Diamino-4-cyclohexenes by Ring Closing Metathesis Reaction

The ring closing metathesis of 4(R),5(R)-bis[1(S)-phenylethylamino]-3,6-diethenyl-1,7-octadiene required the preliminary formation of the cyclic formaldehyde aminal, then the use of the Grubbs' ruthenium benzylidene complex (10 mol %) in refluxing toluene