52144-03-3Relevant articles and documents
N-tetrazolyl quinaldamides
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, (2008/06/13)
Compounds of the general formula (I): SPC1 in which R1, R2 and R3 may be the same or different and each represents a hdyrogen atom, an alkyl group, a nitro group, a halogen atom or a group of the formula --NR4 R5 or --OR4 ; in which the groups R4 and R5 may be the same or different and each represent a hydrogen atom, or an alkyl, alkenyl or cycloalkyl group (which alkyl group may optionally be substituted by alkoxy, hydroxy, amino, alkylamino, dialkylamino or aryl groups) or R4 and R5 together with the nitrogen atom form a heterocyclic ring which may optionally contain additional hetero atoms, e.g. morpholino or piperazinyl; and R6 represents a hydrogen atom or an alkyl group. These compounds have biological activity, particularly in inhibiting the release of spasmogenic substances arising as a consequence of antigen-antibody reactions.