52161-86-1 Usage
Uses
Used in Pharmaceutical Industry:
Baclofen is utilized as a therapeutic agent for the treatment of conditions that cause muscle spasticity, such as multiple sclerosis and spinal cord injury. Its application is based on its ability to bind to GABA-B receptors, which results in the inhibition of excitatory neurotransmission and consequently provides muscle relaxation and spasticity reduction.
Used in Neurological Treatments:
In the field of neurology, baclofen is employed as a muscle relaxant and antispastic medication to alleviate the symptoms of various neurological disorders. Its effectiveness stems from its interaction with GABA-B receptors, which helps in managing and reducing muscle stiffness and spasms associated with these conditions.
Available in Various Administration Forms:
Baclofen is formulated for different modes of administration, including oral and intrathecal, to cater to the varying needs of patients and ensure optimal therapeutic outcomes. This versatility in administration options allows for tailored treatment approaches based on the severity and nature of the condition being treated.
While generally well-tolerated, baclofen may cause side effects such as drowsiness, dizziness, and muscle weakness, which are important considerations in its usage and dosage determination.
Check Digit Verification of cas no
The CAS Registry Mumber 52161-86-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,1,6 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 52161-86:
(7*5)+(6*2)+(5*1)+(4*6)+(3*1)+(2*8)+(1*6)=101
101 % 10 = 1
So 52161-86-1 is a valid CAS Registry Number.
52161-86-1Relevant academic research and scientific papers
Synthesis and Resolution of 3-Substituted Morpgoline Appetite Suppressants and Chiral Synthesis via O-Arylhomoserines
Brown, George R.,Foubister, Alan J.,Stribling, Donald
, p. 547 - 552 (2007/10/02)
The synthesis and resolution of potential appetite suppressant 3-(2-aryloxyethyl)morpholines is described.Assignment of the absolute configuration of the resolved enantiomers is based on a chiral synthesis from O-phenylhomoserines of known configuration.A
