5217-59-4Relevant academic research and scientific papers
Synthetic Versatility of β-Alkoxyvinyl Trichloromethyl Ketones for Obtaining [1,2,4]Triazolo[1,5- a ]pyrimidines
Souza, Laura A.,Santos, Josiane M.,Mittersteiner, Mateus,Andrade, Valquiria P.,Lobo, Marcio M.,Santos, Felipe B.,Bortoluzzi, Adailton J.,Bonacorso, Helio G.,Martins, Marcos A. P.,Zanatta, Nilo
, p. 3686 - 3695 (2018/07/21)
The synthetic versatility of 4-alkoxy-4-alkyl/aryl-1,1,1-trichloroalk-3-en-2-ones (enones) for the synthesis of [1,2,4]triazolo[1,5- a ]pyrimidines, in which the trichloromethyl group is either maintained or eliminated from the product by simply controlli
NMR determination of the structure of azolopyrimidines produced from reaction of bidentate electrophiles and aminoazoles
Hassaneen, Huwaida M. E.,Hassaneen, Hamdi M.,Khiry, Sherif F. M.,Pagni, Richard M.
experimental part, p. 217 - 222 (2008/10/09)
A variety of aminoazoles were reacted with bidentate electrophiles producing azolopyrimidines. The regioselectivity of the nucleophilic attack could be defined from the 13C chemical shift of the pyrimidine carbons and through NOE experiments.
