52176-11-1Relevant academic research and scientific papers
Atropisomerism in aryl-substituted borazines
Allaoud,Frange
, p. 2520 - 2523 (2008/10/08)
The N,N′,N″-tri-o-tolylborazines (o-CH3C6H4NBX)3 (X = Cl, Br, Me, Et) were prepared and studied by means of 1H and 13C NMR. The methyl derivative (X = Me) resulting from the reaction of CH3MgI on the B,B′,B″-trichloro-N,N′,N″-tri-o-tolyl-borazine (X = Cl) in diethyl ether was shown to be a mixture of the cis isomer alone with B-hydroxy byproducts that were identified. This methylation reaction fails to provide the expected trans isomer for steric reasons: instead, B-hydroxy compounds appear during the hydrolysis step.
