52178-87-7

Basic information

• Product Name: 2-[4-(2,2-difluorocyclopropyl)phenoxy]-2-methylpropanoic acid
• CAS NO: 52178-87-7
• Molecular Formula: C₁₃H₁₄F₂O₃
• Molecular Weight: 256.2453
• Mol File: 52178-87-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 359.5°C at 760 mmHg
• Flash Point: 171.2°C
• Density: 1.29g/cm³
• Vapor Pressure: 8.54E-06mmHg at 25°C
• Refractive Index: 1.524
• CAS DataBase Reference: 2-[4-(2,2-difluorocyclopropyl)phenoxy]-2-methylpropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(2,2-difluorocyclopropyl)phenoxy]-2-methylpropanoic acid(52178-87-7)
• EPA Substance Registry System: 2-[4-(2,2-difluorocyclopropyl)phenoxy]-2-methylpropanoic acid(52178-87-7)

Safety Data

• Hazardous Substances Data: 52178-87-7(Hazardous Substances Data)

Relevant articles and documents

Halocyclopropyl substituted phenoxyalkanoic acids

Halocyclopropyl substituted phenoxyalkanoic acids and esters thereof, having hypocholesteremic activity are prepared via several alternative synthetic approaches, involving as the key reactions interaction of a substituted phenylalkene with a carbene source to introduce the halocyclopropyl moiety, and reaction of a substituted phenol with chloroform and a lower-alkanone in the presence of base, or with a lower-alkyl α-bromo-alkanoate, to form the phenoxyalkanoic acid moiety.