5218-24-6Relevant academic research and scientific papers
Synthesis and anticonvulsant activity of some 1,2,3,3α-tetrahydropyrrolo[2,1-b]-benzothiazol-, -thiazol- or -oxazol-1-ones in rodents
Trapani, Giuseppe,Franco, Massimo,Latrofa, Andrea,Carotti, Angelo,Cellamare, Saverio,Serra, Mariangela,Ghiani, Cristina A.,Tuligi, Graziella,Biggio, Giovanni,Liso, Gaetano
, p. 834 - 840 (1996)
To identify more potent anticonvulsant agents and to gain insights into the structural properties determining the potency of a new class of anticonvulsants, some 3α-substituted tetrahydropyrrolo[2,1-b]benzothiazol-1-ones (1a-d) and the thiazole and oxazol
Synthesis and anticonvulsant activity of some 1,2,3,3a-tetrahydropyrrolol[2,1-b]benzothiazol-1-ones and pyrrolo[2,1-b]thiazole analogues
Trapani,Franco,Latrofa,Genchi,Siro Brigiani,Mazzoccoli,Persichella,Serra,Biggio,Liso
, p. 197 - 204 (2007/10/02)
Tetrahydropyrrolo[2,1-b]benzothiazol-1-ones 2a-1 and its analogues 3a-d were synthesized and tested as anticonvulsant agents. Some of the compounds were effective against bicuculline-induced seizures in mice. Binding studies with the prepared compounds us
