5218-51-9 Usage
General Description
(17beta)-17-hydroxyestra-5(10),9(11)-dien-3-one, also known as 17β-hydroxyestradiol, is a synthetic form of the natural female hormone estrogen. It is a derivative of estradiol, the primary female sex hormone, and is often used in hormone replacement therapy to treat symptoms of menopause, such as hot flashes and vaginal dryness. It can also be used as a component of some birth control pills and in the treatment of certain forms of breast cancer. When used in hormone replacement therapy, 17β-hydroxyestradiol works to supplement the body's natural estrogen levels, helping to alleviate symptoms caused by a decrease in estrogen production. However, it is important for individuals to consult with a healthcare professional before using this hormone, as it may have potential side effects and interactions with other medications.
Check Digit Verification of cas no
The CAS Registry Mumber 5218-51-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,1 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5218-51:
(6*5)+(5*2)+(4*1)+(3*8)+(2*5)+(1*1)=79
79 % 10 = 9
So 5218-51-9 is a valid CAS Registry Number.
5218-51-9Relevant articles and documents
Williams et al.
, p. 102,104 (1977)
Method for preparing pufferone acetate (by machine translation)
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Paragraph 0047-0054, (2019/11/21)
The invention discloses a method for preparing pufferone acetate, and belongs to the technical field of preparation and processing of hormone drugs. The process is carried out 3 - with ethylenedioxy estra-Δ. 5,10 , Δ9,11 -17-ketone is a starting raw material, and the preparation of the 3 botanerone acetate is carried out by 17 reducing the position of the ketone as an alcohol, hydrolyzing the position of the furanone, the 17 oxidative dehydrogenation, and the alcohol acetylation. The method has the advantages of cheap and easily available raw materials, simple reaction control, few byproducts, easy purification and high total yield, has extremely high competitiveness in production cost and operability, is suitable for industrial large-scale production and has good economic benefits. (by machine translation)
