52182-27-1Relevant academic research and scientific papers
Domino-Fluorination-Protodefluorination Enables Decarboxylative Cross-Coupling of α-Oxocarboxylic Acids with Styrene via Photoredox Catalysis
Zhang, Muliang,Xi, Junwei,Ruzi, Rehanguli,Li, Nan,Wu, Zhongkai,Li, Weipeng,Zhu, Chengjian
, p. 9305 - 9311 (2017/09/25)
Domino-fluorination-protodefluorination decarboxylative cross-coupling of α-keto acids with styrene has been developed via photoredox catalysis. The critical part of this strategy is the formation of the carbon-fluorine (C-F) bond by the capture of a carbon-centered radical intermediate, which will overcome side reactions during the styrene radical functionalization process. Experimental studies have provided evidence indicating a domino-fluorination-protodefluorination pathway with α-keto acid initiating the photoredox cycle. The present catalytic protocol also affords a novel approach for the construction of α,β-unsaturated ketones under mild conditions.
Iron-oxide nanoparticles mediated cyclization of 3-(4-chlorophenyl)-1- hydrazinylisoquinoline to 1-(4,5-dihydropyrazol-1-yl)isoquinolines
Nawaz Khan,Manivel,Prabakaran,Jin, Jong Sung,Jeong, Euh Duck,Kim, Hyun Gyu,Maiyalagan
experimental part, p. 571 - 582 (2012/06/01)
Iron-oxide nanoparticles were obtained using chitosan templates and their crystalline character and particle size have been confirmed through powder x-ray diffraction and transmission electron microscopy measurements. The particle sizes were found to be 10-25 nm. The diversified chalcones 2 were reacted with 1-hydrazinylisoquinoline 1 in the presence of iron-oxide nanoparticles to the corresponding pyrazolines 3a-j in high yield and purity. The pyrazolines were characterized by spectroscopic techniques. Springer Science+Business Media B.V. 2011.
