52185-25-8Relevant articles and documents
Preparation of 2-phenylsemicarbazides
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, (2008/06/13)
2-Phenylsemicarbazides are prepared by a multi-step process involving: (a) treating a phenylhydrazine, or salt thereof, with a chloroformate; (b) adding phosgene; (c) treating the resulting product with an amine; and (d) hydrolyzing the resulting acylated semicarbazide. The reaction can proceed through a Δ2 -1,3,4-oxadiazolin-5-one intermediate formed with heating in step (b). Certain of the products are novel compounds.