521944-83-2Relevant articles and documents
Study of the heterocyclization of vic-substituted hydrazides of acetylenylpyrazolecarboxylic acids into N-amino pyrazolopyridinones
Vasilevsky, Sergei F.,Mshvidobadze, Elena V.,Elguero, Jose
, p. 1229 - 1233 (2007/10/03)
We report a new and efficient methodology to prepare N-amino pyrazolo[4,3-c]pyridin-4-ones 4 and N-amino pyrazolo[3,4-c]pyridin-4-ones 8 from vic-acetylenyl/hydrazido pyrazoles. The procedure involves the intermediate synthesis of methyl esters of acetylenyl-pyrazole carboxylic acids and the subsequent cyclization under a variety of conditions.