521955-78-2

Upstream product

• 38473-89-1 3-bromo-4-(tert-butyl)benzoic acid 

Downstream Products

• 927436-29-1 (2S,4S,5R)-4-(aminocarbonyl)-1-(3-bromo-4-tert-butylbenzoyl)-2-isobutyl-5-(1,3-thiazol-2-yl)-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 932400-12-9 (2R,4S,5R)-1-(3-bromo-4-tert-butylbenzoyl)-2-(1H-pyrazol-1-yl-methyl)-5-(1,3-thiazol-2-yl)pyrrolidine-2,4-dicarboxylic acid, 2-tert-butyl ester, 4-methyl ester 
• 1258283-75-8 5-dimethylamino-pentanoic acid {4-[3-(3-bromo-4-tert-butyl-benzoyl)-thioureido]-phenyl}-amide hydrochloride 
• 687637-13-4 2-allyl-1-(3-bromo-4-tert-butylbenzoyl)-pyrrolidine-2-carboxylic acid 

Relevant academic research and scientific papers

PYRROLIDINE DERIVATIVES FOR TREATING VIRAL INFECTIONS

Anti-viral agents of Formula (Ia): wherein A represents hydroxy; D represents 3-bromo-4-tert-butylphenyl or 5-bromo-4-tert-butyl-2-fluorophenyl; E represents 1,3-thiazol-2-yl or 5-methylisoxazol-3-yl; G represents methoxymethyl; J represents 1,3-thiazol-4

C (2) -HETEROARYLMETHYL-C (4) -PYRAZINYL-2-YL ACYL PYRROLIDINE COMPOUNDS AND THEIR USE FOR TREATING VIRAL INFECTIONS, ESPECIALLY HEPATITIS C VIRUS

Anti-viral agents of Formula (Ia) : wherein A represents hydroxy; B represents -C(O)R3; D represents 1,3-thiazol-2-yl or 5-methylisoxazol-3-yl; E represents pyrazin-2-yl; G represents 1,3-thiazol-4-ylmethyl or 1H-pyrazol-1-ylmethyl; R3 /s