522-48-5

Basic information

• Product Name: 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole hydrochloride
• Synonyms: TETRAHYDROZOLINE HCL;TETRAHYDROZOLINE HYDROCHLORIDE;2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazolinehydrochloride;2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazolinemonohydrochloride;2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazolinhydrochloride;4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1h-imidazolmonohydroch;4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1h-imidazolmonohydrochlo;dl-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazolinehydrochloride
• CAS NO: 522-48-5
• Molecular Formula: C13H17ClN2
• Molecular Weight: 236.74
• EINECS: 208-329-3
• Product Categories: Adrenergics;Agonists;Neurotransmitters;Intermediates & Fine Chemicals;Pharmaceuticals;VISINE;Pharmaceutical intermediates;Inhibitors
• Mol File: 522-48-5.mol

Chemical Properties

• Melting Point: 248-251°C
• Boiling Point: 393.5 °C at 760 mmHg
• Flash Point: 191.8 °C
• Appearance: off-white solid
• Storage Temp.: Refrigerator
• Solubility: H2O: freely soluble
• CAS DataBase Reference: 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole hydrochloride(522-48-5)
• EPA Substance Registry System: 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole hydrochloride(522-48-5)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: NJ4550000
• Hazardous Substances Data: 522-48-5(Hazardous Substances Data)

Usage

Uses

An alpha agonist, causing constriction of conjunctival blood vessels. Used in over-the-counter eye drops, this compound relieves the redness left by ocular irritants.

Uses

adrenergic agonist, nasal decongestant

Brand name

Tetryzo- line is INN and BAN; Tetryzoline Hydrochloride is JAN; Tetrahydrozoline Nitrate is JAN.

Chemical Properties

Off-White Solid

InChI:InChI=1/C13H16N2.ClH/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13;/h1-2,4,6,12H,3,5,7-9H2,(H,14,15);1H

Upstream product

• 52248-38-1 [2S-(2alpha,4alpha,5alpha,6beta)]-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-oxide 
• 52248-05-2 2,4-diamino-3,5-dihydroxy-6-(pentofuranosyloxy)cyclohexyl 2,6-diamino-2,6-dideoxyhexopyranoside 
• 52248-03-0 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate 
• 52247-86-6 Cicloxolone 
• 52247-81-1 dihydrokawain-5-ol 
• 52247-80-0 (5S,6S)-5,6-Dihydro-5-hydroxy-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one 
• 52247-79-7 (5R,6S)-5,6-Dihydro-5-hydroxy-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one 
• 52247-77-5 (S)-(+)-2-Amino-2-phenylbutyric acid 
• 52247-59-3 1,3-Benzenedicarboxylic acid, polymer with 1,4-benzenedicarboxylic acid, 2,2-dimethyl-1,3-propanediol, 2-ethyl-2-(hydroxymethyl)-1,3-propanediol and hexanedioic acid 
• 52247-47-9 N-[1-[(benzylamino)carbonyl]-2-(1,3-diphenyl-1H-pyrazol-4-yl)vinyl]benzamide 
• 522-47-4 LOCHNERINE 
• 5224-72-6 6-amino-4-(3,4-dimethoxyphenyl)-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile 
• 5224-71-5 6-amino-4-(3-hydroxyphenyl)-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile 
• 52246-55-6 Benzoic acid, 2-[[4-chloro-6-[[3-[[8-[[4-chloro-6-(methylphenylamino)-1,3,5-triazin-2-yl]amino]-1-hydroxy-3,6-disulfo-2-naphthalenyl]azo]-4-sulfophenyl]amino]-1,3,5-triazin-2-yl]amino]-5-sulfo-, tetrasodium salt 

Downstream Products

• 52248-54-1 (22E)-stigmasta-5,7,22-trien-3-ol 
• 52249-32-8 5-Methyl-5H-dibenz[b,f]azepine 
• 52249-48-6 2-Quinolineacetic acid methyl ester 
• 52249-53-3 ethyl 1-phenylpyrrolo[1,2-a]quinoline-3-carboxylate 
• 52249-85-1 1-[4-(BENZYLOXY)-2-HYDROXY-3-METHOXYPHENYL]ETHAN-1-ONE 
• 52249-86-2 1-[2-(BENZYLOXY)-4-METHOXYPHENYL]ETHAN-1-ONE 
• 52249-89-5 3-[6-(benzyloxy)-1,3-benzodioxol-5-yl]-1-[2-(benzyloxy)-4-methoxyphenyl]prop-2-en-1-one 
• 52250-32-5 furo[2,3-f][1,3]benzodioxol-7-yl(2-hydroxy-4-methoxyphenyl)methanone 
• 52250-35-8 ISOMUCRONULATOL 
• 52250-41-6 glycerol propyl ether 
• 52250-44-9 (2R,3R,4R,5R)-5-({[{[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}methyl)-2-(6-amino-9H-purin-9-yl)-4-hydroxytetrahydrofuran-3-yl (2S)-2-amino-3-phenylpropanoate (non-preferred name) 
• 52250-47-2 2-ethyl-2-(3-hydroxypropyl)propanedioic acid 
• 52250-50-7 1-Phenyl-3,4-dihydroisoquinoline 
• 52250-51-8 1-phenyl-3,4-dihydroisochinoline hydrochloride