Welcome to LookChem.com Sign In|Join Free

CAS

  • or

52208-11-4

Post Buying Request

52208-11-4 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

52208-11-4 Usage

General Description

2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl carbamimidothioate is a chemical compound with the molecular formula C11H11N3O2S, which is also known as thionamidilic methyl ester. It is a carbamate derivative and a potent inhibitor of carboxypeptidase A. 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl carbamimidothioate has been studied for its potential pharmaceutical applications, particularly as an anti-cancer agent. Additionally, it has been found to exhibit anti-inflammatory and immunomodulatory properties. However, further research is needed to fully understand its biological activities and potential therapeutic uses.

Check Digit Verification of cas no

The CAS Registry Mumber 52208-11-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,2,0 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 52208-11:
(7*5)+(6*2)+(5*2)+(4*0)+(3*8)+(2*1)+(1*1)=84
84 % 10 = 4
So 52208-11-4 is a valid CAS Registry Number.

52208-11-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(1,3-dioxoisoindol-2-yl)ethyl carbamimidothioate,hydrobromide

1.2 Other means of identification

Product number -
Other names Pseudourea,3-dioxo-2-isoindolinyl)ethylthio-,hydrobromide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52208-11-4 SDS

52208-11-4Downstream Products

52208-11-4Relevant articles and documents

Convenient and environment-friendly synthesis of sulfonyl chlorides from S -alkylisothiourea salts via N-chlorosuccinimide chlorosulfonation

Yang, Zhanhui,Xu, Jiaxi

, p. 1675 - 1682 (2013/07/27)

A convenient, practical, and environmentally friendly method for the synthesis of sulfonyl chlorides has been developed. Structurally diverse sulfonyl chlorides were synthesized in moderate to excellent yields from S-alkylisothiourea salts, which can be easily prepared from readily accessible alkyl halides or mesylates and inexpensive thiourea, via N-chlorosuccinimide chlorosulfonation. In large-scale syntheses, the byproduct succinimide from 'waste water' can be conveniently converted into the starting reagent N-chlorosuccinimide with sodium hypochlorite (bleach) to make the method sustainable. Georg Thieme Verlag Stuttgart, New York.

β-Cyclodextrin derivatives that inhibit anthrax lethal toxin

Karginov, Vladimir A.,Yohannes, Adiamseged,Robinson, Tanisha M.,Fahmi, Nour Eddine,Alibek, Kenneth,Hecht, Sidney M.

, p. 33 - 40 (2007/10/03)

Recently, we demonstrated that simultaneous blocking of bacterial growth by antibiotics and inhibition of anthrax toxin action with antibodies against protective antigen were beneficial for the treatment of anthrax. The present study examined the hypothesis that blocking the pore formed by protective antigen can inhibit the action of anthrax toxin. The potential inhibitors were chosen by a structure-based design using β-cyclodextrin as the starting molecule. Several β-cyclodextrin derivatives were evaluated for their ability to protect RAW 264.7 cells from the action of anthrax lethal toxin. Per-substituted aminoalkyl derivatives displayed inhibitory activity and were protective against anthrax lethal toxin action at low micromolar concentrations. These results provide the basis for a structure-based drug discovery program, with the goal of identifying new drug candidates for anthrax treatment.

Search for cyclodextrin-based inhibitors of anthrax toxins: Synthesis, structural features, and relative activities

Karginov, Vladimir A.,Nestorovich, Ekaterina M.,Yohannes, Adiamseged,Robinson, Tanisha M.,Fahmi, Nour Eddine,Schmidtmann, Frank,Hecht, Sidney M.,Bezrukov, Sergey M.

, p. 3740 - 3753 (2007/10/03)

Recently, using structure-inspired drug design, we demonstrated that aminoalkyl derivatives of β-cyclodextrin inhibited anthrax lethal toxin action by blocking the transmembrane pore formed by the protective antigen (PA) subunit of the toxin. In the prese

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 52208-11-4