Basic information

Product Name: Z-D-LEU-ONP
Synonyms: Z-D-LEU-ONP;Z-D-LEUCINE-ONP;Z-D-LEUCINE 4-NITROPHENYL ESTER;BENZYLOXYCARBONYL-D-LEUCINE P-NITROPHENYL ESTER;BENZYLOXYCARBONYL-D-LEUCINE 4-NITROPHENYL ESTER;N-alpha-Benzyloxycarbonyl-D-leucine p-nitrophenyl ester;(R)-Z-2-amino-4-methyl-pentanoic acid 4-nitrophenyl ester;Z-D-leucine 4-nitrophenyl ester≥ 99% (HPLC)
CAS NO:52235-17-3
Molecular Formula: C₂₀H₂₂N₂O₆
Molecular Weight: 386.4
EINECS: N/A
Product Categories: Amino Acid Derivatives
Mol File: 52235-17-3.mol

Chemical Properties

Melting Point: N/A
Boiling Point: 561.3±45.0 °C(Predicted)
Flash Point: N/A
Appearance: /
Density: 1.239±0.06 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: -15°C
Solubility: N/A
PKA: 10.66±0.46(Predicted)
CAS DataBase Reference: Z-D-LEU-ONP(CAS DataBase Reference)
NIST Chemistry Reference: Z-D-LEU-ONP(52235-17-3)
EPA Substance Registry System: Z-D-LEU-ONP(52235-17-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 52235-17-3(Hazardous Substances Data)

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52235-17-3 Usage

Uses

Used in Biochemistry Research:
Z-D-LEU-ONP is utilized as a substrate for peptidases and proteases, serving as a valuable tool for studying enzymatic reactions and protein interactions. Its chromophoric and fluorescent properties allow for the monitoring of enzyme activity and kinetics, providing insights into the mechanisms of these enzymes.
Used in Drug Development:
In the pharmaceutical industry, Z-D-LEU-ONP is employed as a substrate for the development and screening of enzyme inhibitors. Its unique properties enable the assessment of inhibitory effects on specific peptidases and proteases, aiding in the discovery of potential therapeutic agents targeting these enzymes.
Used in Enzyme Kinetics Studies:
Z-D-LEU-ONP is used as a model substrate to investigate enzyme kinetics, including the determination of Michaelis-Menten constants (Km) and maximum reaction velocities (Vmax). This information is crucial for understanding the efficiency and specificity of enzymes, which can inform the design of enzyme-targeted drugs.
Used in Protein Interaction Analysis:
The fluorescent tag of Z-D-LEU-ONP allows it to be used in assays that study protein-protein interactions, such as fluorescence resonance energy transfer (FRET) experiments. This application helps elucidate the binding mechanisms and affinities of proteins involved in various biological processes.

Check Digit Verification of cas no

The CAS Registry Mumber 52235-17-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,2,3 and 5 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 52235-17:
(7*5)+(6*2)+(5*2)+(4*3)+(3*5)+(2*1)+(1*7)=93
93 % 10 = 3
So 52235-17-3 is a valid CAS Registry Number.

52235-17-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name	(4-nitrophenyl) (2R)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoate

1.2 Other means of identification

Product number	-
Other names	AmbotzZAA1205

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52235-17-3 SDS

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