52248-74-5

Upstream product

• 94161-81-6 2-allyl-1-(ethoxycarbonyl)-1,2-dihydropyridine 

Downstream Products

• 70525-38-1 (E)-2-(2-phenylprop-1-en-1-yl)pyridine 
• 100189-67-1 (2S,3R,4R)-2-Amino-4-hydroxy-3-methyl-N-((S)-1-phenyl-ethyl)-4-pyridin-2-yl-butyramide 
• 100189-67-1 (2R,3R,4R)-2-Amino-4-hydroxy-3-methyl-N-((S)-1-phenyl-ethyl)-4-pyridin-2-yl-butyramide 
• 100189-67-1 (2S,3S,4S)-2-Amino-4-hydroxy-3-methyl-N-((S)-1-phenyl-ethyl)-4-pyridin-2-yl-butyramide 
• 100189-67-1 (2R,3S,4S)-2-Amino-4-hydroxy-3-methyl-N-((S)-1-phenyl-ethyl)-4-pyridin-2-yl-butyramide 
• 100189-64-8 4-Methyl-5-pyridin-2-yl-4,5-dihydro-isoxazole-3-carboxylic acid ((S)-1-phenyl-ethyl)-amide 
• 100189-64-8 4-Methyl-5-pyridin-2-yl-4,5-dihydro-isoxazole-3-carboxylic acid ((S)-1-phenyl-ethyl)-amide 

Relevant academic research and scientific papers

Cycloplatinated(II) complex bearing 2-vinylpyridine and monodentate phosphine ligands: Optical properties and kinetic study

The 2-vinylpyridinate complex [PtMe(Vpy)(DMSO)], C, is successfully prepared from dimeric platinum(II) complex cis,cis-[Me2Pt(μ-SMe2)2PtMe2], B, in the presence of DMSO and 2-vinylpyridine ligand. The DMSO molecule in complex C can be readily substituted by methyldiphenylphosphine (PPh2Me), allowing synthesis of [PtMe(Vpy)(PPh2Me)], 1, which has been fully characterized spectroscopically. Complex 1 is emissive in solid state and solution at room temperature and at 77 K. This complex displays an intense phosphorescence emission (with a significantly long lifetime) which is originated from mixed 3ILCT/3MLCT excited state. Additionally, complex 1 undergoes oxidative addition with alkyl halide (MeI) bearing [PtMe2I(Vpy)(PPh2Me)], 2, after 2 h. Kinetic studies suggest that the latter reaction (oxidative addition) proceed by a classical SN2 mechanism. The rate of oxidative addition reaction at different temperatures is measured and high negative ΔS# value is obtained for the reaction which supported the proposed mechanism. On the basis of NMR spectroscopy, when complex 1 reacts with MeI under extended time (5 days), complex 2 gradually converts to a mixture of platinum complexes trans-[PtMeI(PPh2Me)2], 3, [{PtMe2(Vpy)2(μ-I)2], 4, and a free ligand Z/E-[C8H9N], 5, based on the carbon-carbon bond coupling.

Synthese regioselective par voie organometallique de pyridines, 4-picolines et 3,5-lutidines substituees en 2 par un groupe insature et/ou fonctionnel

A regioselective one-pot synthesis of 2-substituted pyridine derivatives from N-alkoxycarboxylpyridinium salts and α-unsaturated organozinc compounds is described.Similarly, functional alkynyl organomagnesium compounds lead to 2-alkynyl-ω-functional pyridines, from which (E)-2-alkenyl or 2-alkyl-ω-functional pyridines can be obtained by partial or complete reduction.