522601-20-3Relevant academic research and scientific papers
Diverse organo-peptide macrocycles via a fast and catalyst-free oxime/intein-mediated dual ligation
Satyanarayana, Maragani,Vitali, Francesca,Frost, John R.,Fasan, Rudi
, p. 1461 - 1463 (2012/03/26)
Macrocyclic Organo-Peptide Hybrids (MOrPHs) can be prepared from genetically encoded polypeptides via a chemoselective and catalyst-free reaction between a trifunctional oxyamino/amino-thiol synthetic precursor and an intein-fusion protein incorporating a bioorthogonal keto group.
Microwave-assisted synthesis of unnatural amino acids
Young, Douglas D.,Torres-Kolbus, Jessica,Deiters, Alexander
experimental part, p. 5478 - 5480 (2009/05/30)
Microwave irradiation has been proven to be a useful tool in the rapid assembly of racemic unnatural amino acids in only two steps. Additional benefits of this methodology are the commercial availability of the inexpensive starting materials and the high yields and high purities of the final amino acid products.
Protein arrays
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, (2008/06/13)
The invention provides proteins attached to solid supports, and methods of preparing such solid support-bound proteins are provided. The proteins are attached to solid supports by means of an unnatural amino acid incorporated into the protein, which unnat
