52271-42-8 Usage
Uses
Used in Pharmaceutical Research:
3,4-Methylenedioxybenzyl methyl ketoximine is used as a research chemical for studying the effects of psychoactive substances on the brain and their potential therapeutic applications. It is particularly valuable in investigating the interactions between neurotransmitters and their transporters, which can provide insights into the development of new treatments for psychiatric disorders.
Used in Medicinal Chemistry:
3,4-Methylenedioxybenzyl methyl ketoximine is used as a starting material or intermediate in the synthesis of other psychoactive compounds with potential therapeutic benefits. Its unique interaction with neurotransmitter transporters makes it a valuable tool in the development of new medications for the treatment of various psychiatric conditions.
Used in Neuroprotective and Antioxidant Studies:
3,4-Methylenedioxybenzyl methyl ketoximine is used as a subject of research in the field of neuroprotection and antioxidant properties. Its potential to protect neurons and reduce oxidative stress in the brain makes it an interesting candidate for the development of treatments aimed at preventing or slowing the progression of neurodegenerative diseases.
Note: It is important to emphasize that 3,4-Methylenedioxybenzyl methyl ketoximine is a psychoactive substance and its recreational use can have serious health risks and legal consequences. The information provided here is for educational purposes and should not be interpreted as an endorsement or promotion of its use outside of controlled research settings.
Check Digit Verification of cas no
The CAS Registry Mumber 52271-42-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,2,7 and 1 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 52271-42:
(7*5)+(6*2)+(5*2)+(4*7)+(3*1)+(2*4)+(1*2)=98
98 % 10 = 8
So 52271-42-8 is a valid CAS Registry Number.
52271-42-8Relevant academic research and scientific papers
Indium-mediated reduction of β-nitrostyrenes to oximes in aqueous media
Yadav,Subba Reddy,Srinivas,Ramalingam
, p. 1447 - 1449 (2007/10/03)
β-Nitrostyrenes are selectively reduced to the corresponding oximes in high yields by indium metal in aqueous methanol under neutral reaction conditions.
Reduction of conjugated nitroalkenes with zinc borohydride. A mild method for converting monosubstituted nitroalkenes to nitroalkanes and disubstituted ones to oximes
Ranu,Chakraborty
, p. 5317 - 5322 (2007/10/02)
Mono-β-substituted conjugated nitroalkenes are readily reduced by zinc borohydride in 1,2-dimethoxyethane to the corresponding nitroalkanes, whereas the disubstituted ones furnish the corresponding oximes in excellent yields.
Highly Selective Reduction of Conjugated Nitroalkenes with Zinc Borohydride in DME
Ranu, Brindaban C.,Chakraborty, Rupak
, p. 3579 - 3582 (2007/10/02)
Zinc borohydride in 1,2-dimethoxyethane reduces α-substituted conjugated nitroalkenes to the corresponding oximes and non-α-substituted ones to the corresponding nitroalkanes in excellent yields.
Centrally active N-substituted analogs of 3,4-methylenedioxyphenylisopropylamine (3,4-methylenedioxyamphetamine)
Braun,Shulgin,Braun
, p. 192 - 195 (2007/10/02)
The known central nervous system activity of 3,4-methylenedioxyphenylisopropylamine and its N-methyl homolog prompted the synthesis of a series of analogs with substituents on the nitrogen atom. Most of these analogs (R = alkyl, alkenyl, hydroxy, alkoxy, and alkoxyalkyl) were prepared by the reductive alkylation of 3,4-methylenedioxyphenylacetone with the appropriate amine and sodium cyanoborohydride. Hindered isomers were synthesized indirectly. Measurements of their pharmacological activity in several animal assays and in human subjects indicated that the central activity decreased with the increasing bulk of the N-substituent.
