52273-74-2

Upstream product

• 52273-70-8 N-[4-(3-chloropropyl)-2-nitrophenyl]acetamide 
• 52273-68-4 4-(3-chloropropyl)acetanilide 

Downstream Products

• 394203-88-4 2-nitro-4-[3-(4-phenylpiperazin-1-yl)propyl]phenylamine 
• 856400-04-9 2-nitro-4-{3-[4-(4-chlorophenyl)piperazin-1-yl]propyl}aniline 
• 856400-06-1 2-nitro-4-{3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl}aniline 
• 856400-08-3 2-nitro-4-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}aniline 
• 856400-02-7 2-nitro-4-(3-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}propyl)aniline 
• 394203-89-5 4-[3-(4-phenyl-piperazin-1-yl)-propyl]-benzene-1,2-diamine 

Relevant academic research and scientific papers

HETEROARYL PROPYL-PIPERAZINES AND HETEROARYL PROPYL-PIPERIDINES

The invention relates to novel compounds of 4-[3-(4-arylpiperazine-1-yl)-propyl]-benzo-1,2-diamines I, 4-(3-{4-[bis-(4-fluorophenyl)-methyl]-piperidine-1-yl}-propyl)-benzo-1,2-diamine III and 8-[3-(3,4-diaminophenyl)-propyl]-1-phenyl-1,3,8-triaza-spiro[4.

Investigation of mixed D2/5-HT1A activity of N-heteroarylmethyl-N-phenylpiperazines, N-heteroarylethyl-N-phenylpiperazines and N-heteroarylpropyl-N-phenylpiperazines.

Eight novel N-heteroarylalkyl-N-phenylpiperazines have been synthesized, chemically characterized and evaluated for in vitro binding affinity at the dopamine and serotonin receptors. Synaptosomal membranes of fresh bovine caudate nuclei (D1 and D2), the m