52287-58-8

Upstream product

• 79-24-3 Nitroethane 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 75-52-5 nitromethane 
• 960053-43-4 C₉H₉Cl₂NO₃ 

Downstream Products

• 32560-77-3 2-(2,4-dichloro-phenyl)-1-methyl-ethylamine 
• 4380-31-8 [2-bromo-1-(2,4-dichloro-phenyl)-2-nitro-propyl]-methyl ether 
• 1320232-30-1 C₂₀H₁₇Cl₂NO₂ 
• 1374229-55-6 ethyl 4-(2,4-dichlorophenyl)-2,5-dimethylfuran-3-carboxylate 
• 95838-60-1 4-(2,4-Dichlorphenyl)-2,5-dimethyl-3-pyrrolcarbonsaeure-methylester 
• 1374229-54-5 1-[4-(2,4-dichlorophenyl)-2,5-dimethylfuran-3-yl]ethanone 
• 1092400-98-0 2-(2,4-dichloro-phenyl)-2-methoxy-1-methyl-ethylamine 
• 1092400-96-8 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid [2-(2,4-dichlorophenyl)-2-methoxyamino-1-methyl-ethyl]-amide 
• 1092400-95-7 N-[1-(2_,4-dichlorophenyl)-1-methoxypropan-2-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide 
• 1092401-00-7 N-[2-amino-1-(2,4-dichloro-phenyl)-propyl]-O-methyl-hydroxylamine 
• 1426080-01-4 2-(2,4-dichlorophenyl)-3-methylimidazo[1,2-a]pyridine 
• 1092400-97-9 2,4-dichloro-1-(1-methoxy-2-nitro-propyl)-benzene 
• 1092400-99-1 N-[1-(2,4-dichloro-phenyl)-2-nitro-propyl]-O-methyl-hydroxylamine 
• 154-98-3 2-(2,4-dichloro-phenyl)-1-methyl-ethylamine; hydrochloride 

Relevant academic research and scientific papers

Iron-catalyzed tandem one-pot addition and cyclization of the blaise reaction intermediate and nitroolefins: Synthesis of substituted NH-pyrroles from nitriles

The iron-catalyzed addition and cyclization of the Blaise reaction intermediate and nitroolefins to synthesize highly functionalized NH-pyrroles in a tandem one-pot manner from nitriles has been developed. This reaction shows good functional group tolerance and affords a broad spectrum of substituted NH-pyrroles in good yields. Copyright

Adapting to substrate challenges: Peptides as catalysts for conjugate addition reactions of aldehydes to α,β-disubstituted nitroolefins

Conjugate addition reactions of aldehydes to α,β-disubstituted nitroolefins are important because they provide synthetically useful γ-nitroaldehydes bearing three consecutive stereogenic centers. Such reactions are challenging due to the drastically lower reactivity of α,β-disubstituted nitroolefins compared to, for example, β-monosubstituted nitroolefins. The testing of a small collection of peptides of the type Pro-Pro-Xaa (Xaa=acidic amino acid) led to the identification of H-Pro-Pro-D-Gln-OH and H-Pro-Pro-Asn-OH as excellent stereoselective catalysts for this transformation. In the presence of 5a mol% of these peptides different combinations of aldehydes and α,β- disubstituted nitroolefins react readily with each other providing γ-nitroaldehydes in good yields and diastereoselectivities as well as excellent enantioselectivities. Chiral pyrrolidines as well as fully substituted γ-butyrolactams and γ-amino acids are easily accessible from the γ-nitroaldehydes. Mechanistic studies demonstrate that the configuration at all three stereogenic centers is induced by the peptidic catalysts. Only a minimal amount of products from homo-aldol reactions is observed demonstrating the high chemoselectivity of the peptidic catalysts. α,β- Disubstituted nitroolefins are challenging electrophiles due to their low reactivity. The modular nature of peptides of the type Pro-Pro-Xaa (Xaa=acidic amino acid; see scheme) allowed for the identification of H-Pro-Pro-D-Gln-OH and H-Pro-Pro-Asn-OH as very good catalysts for the conjugate addition reaction of aldehydes to α,β-disubstituted nitroolefins. Mechanistic studies demonstrate that the peptides induce the configuration at each of the stereogenic centers. Copyright

Ethylenediamine: A highly effective catalyst for one-pot synthesis of aryl nitroalkenes via henry reaction and dehydration

Ethylenediamine (H2NCH2CH2NH2) was found to be a highly effective catalyst for the condensation of aryl aldehydes with nitromethane (or nitroethane). When 1%-2% (mol%) of ethylenediamine was used as the catalyst, the one-pot reaction of aryl aldehydes with nitromethane (or nitroethane) by refluxing for 3-10 h efficiently afforded various arylnitroalkenes 1a-1y in 85%-97% yields. Ethylenediamine (H 2NCH2CH2NH2) was found to be a highly effective catalyst for the condensation of aryl aldehydes with nitromethane (or nitroethane). When 1-2 mol% of ethylenediamine was used as the catalyst, the one-pot reaction of aryl aldehydes with nitromethane (or nitroethane) by refluxing for 3-10 h efficiently afforded various aryl nitroalkenes 1a-1y in 85%-97% yields. Copyright

NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES

Compounds of formula (I) in which the substituents are as defined in claim 1, are suitable for use as microbiocides.

NOVEL MICROBIOCIDES

Compounds of formula (I) in which the substituents are as defined in claim 1,are suitable for use as microbiocides.

N-2-(HETERO)ARYLETHYLCARBOXAMIDE DERIVATIVE, AND PEST-CONTROLLING AGENT COMPRISING THE SAME

An N-2-(hetero)arylethylcarboxamide derivative represented by the formula (I) wherein R1 and R2 are each independently a hydrogen atom etc., R3 and R4 are each independently a hydrogen atom etc., each Y is indep

Optically active ethyl amides

Compounds of the formula I wherein R1 is C1-C3alkyl, CF3 or CF2H; X1 is hydrogen or fluoro; n is 2 or 3; each X2 independently of each other stands for chloro, bromo, fluoro, CH

PYRAZOLE CARBOXYLIC ACID AMIDES USEFUL AS MICROBIOCIDES

Compounds of the formula (I), in which the substituents are as defined in claim 1 are suitable for use as microbiocides.

N- (L-ALKYL-2- PHENYLETHYL) -CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES

Compounds of the formula (I) in which the substituents are as defined in claim 1 are suitable for use as microbiocides.

1-(2-Propynyl)-1 H-indazole compounds

1-(2-PROPYNYL)-1 H-indazole compounds represented by the formula SPC1 Wherein R represents hydrogen or halogen other than iodine, R1 represents hydrogen or nitro, and R2 represents hydrogen, nitro or halogen other than iodine are dis