52290-88-7Relevant academic research and scientific papers
A speedy route to sterically encumbered, benzene-fused derivatives of privileged, naturally occurring hexahydropyrrolo[1,2-b]isoquinoline
Bakulina, Olga,Ivanov, Alexander,Suslonov, Vitalii,Darin, Dmitry,Krasavin, Mikhail
, p. 1413 - 1424 (2017/07/28)
A series of 15 benzene-fused hexahydropyrrolo[1,2-b]isoquinolonic acids with substantial degree of steric encumbrance has been prepared via a novel variant of the Castagnoli-Cushman reaction of homophthalic anhydride (HPA) and various indolenines. The employment of a special kind of a cyclic imine component reaction allowed, for the first time, isolating a Mannich-type adduct between HPA and an imine component which has been postulated but never obtained in similar reactions.
New highly diastereoselective Perkin/Michael addition domino reaction between homophthalic anhydride and aromatic aldehydes: A facile approach to blue-fluorescent dibenzo[c,h]chromenones
Bogdanov, Milen G.,Mitrev, Yavor,Tiritiris, Ioannis
supporting information; experimental part, p. 377 - 384 (2011/02/28)
A series of new trans-11-aryl-6-oxo-6H-dibenzo[c,h]chromene-12-carboxylic acids has been synthesised through anew Perkin/Michael addition domino reaction between homophthalic anhydride and aromatic aldehydes. The synthesis is straightforward and gives goo
