17α-Fluoroyohimban is a naturally occurring indole alkaloid found in the bark of the West African tree, Pausinystalia yohimbe. It is structurally similar to yohimbine, a well-known stimulant and aphrodisiac, but with a fluorine atom attached to the 17α position. This modification enhances its potency and selectivity as an α2-adrenergic receptor antagonist, which can lead to increased blood flow and arousal. The compound has been studied for its potential therapeutic applications in treating erectile dysfunction, anxiety, and depression, although its use is not yet widespread and further research is needed to fully understand its safety and efficacy.
523-11-5
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Basic information
- Product Name: 17α-Fluoroyohimban
- Synonyms: 17α-Fluoroyohimban
- CAS NO:523-11-5
- Molecular Formula: C19H23FN2
- Molecular Weight: 298.3977232
- EINECS: N/A
- Product Categories: N/A
- Mol File: 523-11-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 461.7°Cat760mmHg
- Flash Point: 233°C
- Appearance: /
- Density: 1.23g/cm3
- Vapor Pressure: 1.05E-08mmHg at 25°C
- Refractive Index: 1.641
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 17α-Fluoroyohimban(CAS DataBase Reference)
- NIST Chemistry Reference: 17α-Fluoroyohimban(523-11-5)
- EPA Substance Registry System: 17α-Fluoroyohimban(523-11-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 523-11-5(Hazardous Substances Data)
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Chemical compound
17α-Fluoroyohimban is a synthetic chemical compound.Derivative
It is a derivative of yohimbine, an alkaloid found in the bark of the yohimbe tree.Modification
The introduction of a fluorine atom at the 17th position of the yohimbe molecule.Pharmaceutical properties
This modification enhances its pharmaceutical properties.Potency
It can increase its potency.Bioavailability
It can increase its bioavailability.Medical conditions
It has been studied for its potential use in the treatment of various medical conditions, such as erectile dysfunction, obesity, and depression.Therapeutic agent
It is being investigated as a potential therapeutic agent for improving cognitive function and enhancing athletic performance.Mechanism of action
Further research is needed to fully understand its mechanism of action.Safety profile
Further research is needed to fully understand its safety profile.Potential side effects
Further research is needed to fully understand its potential side effects.Check Digit Verification of cas no
The CAS Registry Mumber 523-11-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 3 respectively; the second part has 2 digits, 1 and 1 respectively.Calculate Digit Verification of CAS Registry Number 523-11:
(5*5)+(4*2)+(3*3)+(2*1)+(1*1)=45
45 % 10 = 5
So 523-11-5 is a valid CAS Registry Number.
InChI:InChI=1/C19H23FN2/c20-14-6-5-12-11-22-8-7-16-15-3-1-2-4-17(15)21-19(16)18(22)10-13(12)9-14/h1-4,12-14,18,21H,5-11H2/t12-,13-,14-,18-/m0/s1
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17α-Fluoroyohimban
