52305-20-1

Upstream product

• 29724-89-8 N-((1RS,2RS)-2-chloro-1-methyl-2-phenyl-ethyl)-N-methyl-acetamide 
• 1630-34-8 (1RS:2SR)-2-methylamino-1-acetoxy-1-phenyl-propane; hydrochloride 
• 90-81-3 ephedrine 
• 108-24-7 acetic anhydride 
• 90-82-4 rac-pseudoephedrine 

Downstream Products

• 760188-32-7 (-)-(1'S,1''R,2''R,4R)-4-{1'-hydroxy-2'-[N-(2''-hydroxy-1''-methyl-2''-phenylethyl)-N-methylcarbamoyl]ethyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 1262432-89-2 (-)-(3S,4R)-4-(tert-butoxycarbonyl(methyl)amino)-3-hydroxy-N-methyl-N-((R,R)-2-phenyl-2-hydroxy-1-methylethyl)-5-phenylpentanamide 
• 1262432-78-9 (-)-(S)-3-((R)-2,2-dimethyl[1,3]dioxolan-4-yl)-3-hydroxy-N-((R,R)-1-hydroxy-1-phenylpropan-2-yl)-N-methylpropanamide 
• 1262432-87-0 C₂₅H₃₄N₂O₅ 
• 1262432-86-9 C₂₆H₃₆N₂O₅ 
• 1262432-83-6 (-)-N-tert-butoxycarbonyl-(2R)-{(S)-1-hydroxy-2-[N-((R,R)-2-phenyl-2-hydroxy-1-methylethyl)-N-methylcarbamoyl]ethyl}pyrrolidine 

Relevant academic research and scientific papers

MISE EN EVIDENCE PAR RMN-(1)H ET -(13)C D'ISOMERISME Z/E ET D'EQUILIBRE CONFORMATIONNEL SUR UNE SERIE DE DERIVES MONO- ET DIACETYLES DE 2-ALKYLAMINO-1-PHENYLPROPAN-1-OLS

(1)H- and (13)C NMR studies of mono- and diacetylated-erythro- and threo-2-alkylamino-1-phenylpropan-1-ols, C6H5CHOHCHNHRCH3 (R = H, CH3, C2H5 AND i-C3H7) show that the series exhibit Z/E isomerism about the C-N amide bond.The Z/E ratio increases in the monoacetylated series CH3 1-C2 and N-C2 bonds.In the Z configuration, the conformer Z-s-syn where the proton H-2 is syn with the N-alkyl substituent predominates.