52333-47-8

Basic information

• Product Name: Oxazolo[4,5-b]pyridine, 2-(4-fluorophenyl)-
• Synonyms: HMS1601L18
• CAS NO: 52333-47-8
• Molecular Formula: C12H7FN2O
• Molecular Weight: 214.199
• Mol File: 52333-47-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Oxazolo[4,5-b]pyridine, 2-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazolo[4,5-b]pyridine, 2-(4-fluorophenyl)-(52333-47-8)
• EPA Substance Registry System: Oxazolo[4,5-b]pyridine, 2-(4-fluorophenyl)-(52333-47-8)

Safety Data

• Hazardous Substances Data: 52333-47-8(Hazardous Substances Data)

Upstream product

• 16867-03-1 2-amino-3-hydroxypyridine 
• 459-57-4 4-fluorobenzaldehyde 
• 5153-69-5 4-fluoro-β-nitrostyrene 
• 456-22-4 4-Fluorobenzoic acid 

Downstream Products

• 1380678-08-9 4-((2-(4-fuorophenyl)oxazolo[4,5-b]pyridin-7-yl)oxy)aniline 
• 1380678-09-0 N-((4-((2-(4-fluorophenyl)oxazolo[4,5-b]pyridin-7-yl)oxy)phenyl)carbamothioyl)-2-phenylacetamide 
• 1380678-05-6 C₁₂H₇FN₂O₂ 
• 1380678-06-7 7-chloro-2-(4-fluorophenyl)oxazolo[4,5-b]pyridine 
• 1380678-07-8 2-(4-fluorophenyl)-7-(4-nitrophenoxy)oxazolo[4,5-b]pyridine 

Relevant articles and documents

Molecular modeling, density functional theory, ADME prediction and antimicrobial activity studies of 2-(substituted)oxazolo[4,5-: B] pyridine derivatives

In this study, the antimicrobial activities of previously synthesized 2-(substituted)oxazolo[4,5-b]pyridine derivatives toward six bacteria strains and twelve related drug-resistant isolates, and one fungus strain and two related drug-resistant isolates w

Ce(III)-catalyzed highly efficient synthesis of pyridyl benzamides from aminopyridines and nitroolefins without external oxidants

An efficient synthesis of a variety of pyridyl benzamides from 2-aminopyridines and nitroolefins is described. This rare-earth-metal-catalyzed reaction provides the corresponding products with broad substrate scope in moderate to excellent yields, in the absence of additives and external oxidants. Water is used as the source of the carbonyl oxygen atom in pyridyl benzamides. Furthermore, 2-substituted oxazolo[4,5-b]pyridines are formed in good yields under the standard conditions when 2-aminopyridin-3-ols are used as the substrates.

Anti-inflammatory oxazole[4,5-b]pyridines

The various isomers of oxazolo- and thiazolopyridines having utility as antiinflammatory, antipyretic and analgesic agents are prepared by condensation of an appropriate amino-hydroxypyridine or amino-mercaptopyridine with a carboxylic acid, halide or anhydride.