52333-48-9 Usage
Uses
Used in Medicinal Chemistry:
2-(Pyridin-3-yl)oxazolo[4,5-b]pyridine is utilized as a key intermediate in the synthesis of various pharmaceuticals and bioactive molecules. Its unique structure allows for the creation of compounds with specific biological activities, making it a valuable component in the development of new drugs.
Used in Drug Discovery and Design:
In the pharmaceutical industry, 2-(Pyridin-3-yl)oxazolo[4,5-b]pyridine is employed as a scaffold for designing novel drug candidates. Its heterocyclic nature and the presence of both pyridine and oxazole rings provide a versatile platform for chemical modifications, which can enhance the compound's pharmacological properties and target specific biological pathways.
Used in Research and Development:
2-(Pyridin-3-yl)oxazolo[4,5-b]pyridine serves as a subject of interest in academic and industrial research settings. Its exploration is crucial for understanding its potential biological activities and for identifying new therapeutic applications, thereby contributing to the advancement of medicine and healthcare.
Check Digit Verification of cas no
The CAS Registry Mumber 52333-48-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,3,3 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 52333-48:
(7*5)+(6*2)+(5*3)+(4*3)+(3*3)+(2*4)+(1*8)=99
99 % 10 = 9
So 52333-48-9 is a valid CAS Registry Number.
52333-48-9Relevant academic research and scientific papers
New access to oxazolopyridines via hydroxyamidine derivatives; application to quinolines
Garnier, Ethel,Blanchard, Stephanie,Rodriguez, Ivan,Jarry, Christian,Leger, Jean-Michel,Caubere, Paul,Guillaumet, Gerald
, p. 2033 - 2040 (2007/10/03)
Several 2-aryl and 2-heteroaryloxazolo[4,5-b]pyridines were synthesised in high yields from zwitterion or hydroxyamidine derivatives by heating in dimethylacetamide. These intermediates were generated via hetarynic reaction with the complex base NaNH2-t-BuONa (5:2). The same reactions were possible with quinoline derivatives.
Anti-inflammatory oxazole[4,5-b]pyridines
-
, (2008/06/13)
The various isomers of oxazolo- and thiazolopyridines having utility as antiinflammatory, antipyretic and analgesic agents are prepared by condensation of an appropriate amino-hydroxypyridine or amino-mercaptopyridine with a carboxylic acid, halide or anhydride.
