52368-18-0 Usage
Uses
Used in Pharmaceutical Industry:
2-Pyridinecarboxamide,6-cyano-(9CI) is used as a pharmaceutical intermediate for the development of drugs targeting various diseases. Its potential biological activities, such as antiviral and anticancer properties, make it a valuable compound for further research and development in the pharmaceutical field.
Used in Chemical Industry:
2-Pyridinecarboxamide,6-cyano-(9CI) serves as a key building block in the synthesis of various chemical compounds. Its unique structure and functional groups allow it to be used in the production of a wide range of chemical products, contributing to the advancement of the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 52368-18-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,3,6 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 52368-18:
(7*5)+(6*2)+(5*3)+(4*6)+(3*8)+(2*1)+(1*8)=120
120 % 10 = 0
So 52368-18-0 is a valid CAS Registry Number.
52368-18-0Relevant academic research and scientific papers
Catalytic hydration of cyanopyridines using nickel(0)
Crisóstomo, Carmela,Crestani, Marco G.,García, Juventino J.
experimental part, p. 1092 - 1096 (2010/06/15)
The homogeneous catalytic hydration of 2-, 3- and 4-cyanopyridines using 0.5 mol% of [(dippe)Ni(μ-H)]2 as catalyst precursor was achieved under heating. In the case of 4-cyanopyridine, production of isonicotinamide was observed at temperatures in the range of 80-120 °C. Heating to 180 °C resulted in formation of isonicotinic acid. In the case of 2- and 3-cyanopyridines the quantitative formation of their corresponding amides was achieved at 100 °C. The catalytic hydration of 2,6-dicyanopyridine was also undertaken in this work, in its case resulting in the synthesis of the mixed cyano/amide product, 2-cyanopyridine-6-carboxamide, at short reaction times.