52379-48-3

Upstream product

• 6083-47-2 4-(dimethylamino)benzamide 
• 62-53-3 aniline 
• 1197-19-9 4-cyano-N,N-dimethylaniline 
• 2829-28-9 4-dimethylamino-benzaldehyde phenylhydrazone 

Downstream Products

• 15030-24-7 2-(4-(dimethylamino)phenyl)-1-phenyl-1H-naphtho[2,3-d]imidazole-4,9-dione 
• 1350629-10-5 1-phenyl-2-(4-N,N-dimethylamino-phenyl)-1H-imidazo[4,5-b]pyrazine 
• 1350629-13-8 1-phenyl-2-(4-N,N-dimethylamino-phenyl)-1H-imidazo[4,5-b]quinoxaline 
• 1350629-01-4 1-phenyl-2-(4-N,N-dimethylamino-phenyl)-1H-5-methoxy-benzo[d]imidazole 
• 2562-73-4 1-phenyl-2-(4-N,N-dimethylamino-phenyl)-1H-benzo[d]imidazole 

Relevant academic research and scientific papers

Direct Synthesis of 3-Acylindoles through Rhodium(III)-Catalyzed Annulation of N-Phenylamidines with α-Cl Ketones

In the present study, a novel synthetic strategy to directly produce versatile 3-acylindoles through Rh(III)-catalyzed C-H activation and annulation cascade of N-phenylamidines with α-Cl ketones was developed, in which α-Cl ketones serve as unusual one-carbon (sp3) synthons. This strategy features high regioselectivity, efficiency, wide substrate tolerance, and mild reaction conditions, which further underscore its synthetic utility in drug molecule synthesis.

Regiospecific synthesis of 1, 2-disubstituted (hetero)aryl fused imidazoles with tunable fluorescent emission

A palladium-catalyzed two or fourfold amination was established that allows regiospecific synthesis of a diversity-oriented library of 1, 2 disubstituted (hetero)aryl fused imidazoles, and provides an exceptional tool for the discovery of fluorescent scaf