52386-40-0 Usage
General Description
3-Methyl-1,2,4-oxadiazol-5-ol, also known as moxidectin, is a chemical compound that belongs to the oxadiazole class of organic compounds. It is a synthetic anthelmintic and insecticidal agent that is widely used in veterinary medicine to control internal and external parasites in livestock and companion animals. Moxidectin works by disrupting the nerve transmission in target parasites, leading to paralysis and death. It has a broad spectrum of activity against a wide range of parasites, including gastrointestinal nematodes, lungworms, mites, and lice. Moxidectin is known for its long-lasting efficacy and has become an important tool in parasite control and prevention programs in agricultural and veterinary settings. It is available in various formulations, including oral drenches, injectables, and topical products for easy administration in different animal species.
Check Digit Verification of cas no
The CAS Registry Mumber 52386-40-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,3,8 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 52386-40:
(7*5)+(6*2)+(5*3)+(4*8)+(3*6)+(2*4)+(1*0)=120
120 % 10 = 0
So 52386-40-0 is a valid CAS Registry Number.
52386-40-0Relevant articles and documents
Kinetics of base-catalysed hydrolysis and cyclisation of substituted acetamide and benzamide O-(phenoxycarbonyl)oximes
Mindl, Jaromir,Kavalek, Jaromir,Strakova, Helena,Sterba, Vojeslav
, p. 1641 - 1653 (2007/10/03)
The reaction kinetics of acetamide O-(4-nitrophenoxycarbonyl)oxime have been studied in aqueous buffers at pH 2-11. At pH > 9, the pH dependence of kobs is linear with slope 1, the cyclisation to 3-methyl-1,2,4-oxadiazol-5(4H)-one and 4-nitrophenol being the only reaction. At pH obs on pH has been used to determine the rate equation and to propose the reaction mechanism. The cyclisation kinetics of substituted benzamide O-(phenoxycarbonyl)oximes have been studied in the pH range from 9.25 to 11. The reaction mechanism has been proposed based on the ρ constants found. In the first reaction step, the proton is split off from the NH2 group; the subsequent, rate-limiting step involves simultaneous N-C bond formation and C-O bond splitting.
