52397-81-6

Basic information

• Product Name: 4 6-DICHLORO-1-INDANONE 97
• Synonyms: 4 6-DICHLORO-1-INDANONE 97;4,6-dichloro-2,3-dihydro-1H-inden-1-one;4,6-Dichloro-1-indanone 97%;4,6-dichloro-2,3-dihydroinden-1-one
• CAS NO: 52397-81-6
• Molecular Formula: C9H6Cl2O
• Molecular Weight: 201.051
• Mol File: 52397-81-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 118-123 °C
• Boiling Point: 326℃
• Flash Point: 137℃
• Appearance: /
• Density: 1.447
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.613
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4 6-DICHLORO-1-INDANONE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 4 6-DICHLORO-1-INDANONE 97(52397-81-6)
• EPA Substance Registry System: 4 6-DICHLORO-1-INDANONE 97(52397-81-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 2
• Hazardous Substances Data: 52397-81-6(Hazardous Substances Data)

Usage

General Description

4,6-Dichloro-1-indanone 97 is a chemical compound used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and organic compounds. It is known for its role as a building block in the production of antihypertensive and anti-inflammatory medications. This chemical is classified as a ketone, with two chlorine atoms attached to the 4 and 6 positions of the indanone ring. Due to its versatile reactivity and unique structure, 4,6-Dichloro-1-indanone 97 is a valuable compound in organic synthesis and drug development, making it an important component in the pharmaceutical and chemical industries.

InChI:InChI=1/C9H6Cl2O/c10-5-3-7-6(8(11)4-5)1-2-9(7)12/h3-4H,1-2H2

Upstream product

• 52397-82-7 3-(2,4-dichlorophenyl)propanoyl chloride 
• 1201-99-6 trans-2,4-dichlorocinnamic acid 
• 55144-92-8 3-(2,4-dichlorophenyl)propionic acid 

Downstream Products

• 1215279-81-4 (1aS,6aR)-3,5-dichloro-6,6a-di-hydro-1aH-1-oxa-cyclopropa[a]indene 
• 1215273-25-8 (S)-1-[(1S,2S)-4,6-dichloro-1-(4-methanesulfonylphenoxy)indan-2-yl]-3-fluoropyrrolidine 
• 1215272-30-2 (R)-1-[(1S,2S)-4,6-dichloro-1-(4-methanesulfonylphenoxy)indan-2-yl]-3-fluoropyrrolidine 
• 320419-47-4 4,6-dichloro-2-[1-dimethylaminomethylidene]indan-1-one 
• 1188143-94-3 4,6-dichloroindan-1-ol 
• 55144-55-3 2-bromo-4,6-dichloroindan-1-one 

Relevant articles and documents

Synthesis of Conformationally Locked and C-Linked Analogues of Imidazole-Based Ketene Dithioacetal Fungicides

First examples with the unknown tricyclic 4,8 b -dihydro-3 aH -indeno[1,2- d ][1,3]dithiole ring system have been prepared. Also, imidazoles linked in ring position 5 to a ketene dithioacetal and 1,3-dithiane derivatives with an exocyclic cyano- and imidazole-substituted C-C double bond are completely new. All these compounds are either conformationally locked, C-linked or six-ring analogues of the antifungal agent luliconazole. Synthesis and fungicidal activity of these sterol biosynthesis inhibitors are reported.

Indanylidenes. 2. Design and synthesis of (E)-2-(4-chloro-6-fluoro-1-indanylidene)-N-methylacetamide, a potent antiinflammatory and analgesic agent without centrally acting muscle relaxant activity

Extension of the structure-activity relationship studies that led to the discovery of the nonsedating potent muscle relaxant, antiinflammatory, and analgesic agent (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 1, has given rise to (E)-2-(4-chloro-6-fluoro

Quinolones used as MRS inhibitors and bactericides

Compounds of formula (I) are inhibitors of the bacterial enzymeS aureusmethionyl tRNA synthetase and are of use in treating bacterial infections.