523977-64-2

Basic information

• Product Name: 4-Bromo-2-cyanobenzaldehyde
• Synonyms: 4-Bromo-2-cyanobenzaldehyde;5-Bromo-2-formylbenzonitrile
• CAS NO: 523977-64-2
• Molecular Formula: C₈H₄BrNO
• Molecular Weight: 210.04
• Mol File: 523977-64-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 324℃
• Flash Point: 150℃
• Appearance: /
• Density: 1.65
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-Bromo-2-cyanobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-2-cyanobenzaldehyde(523977-64-2)
• EPA Substance Registry System: 4-Bromo-2-cyanobenzaldehyde(523977-64-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22-43
• Hazardous Substances Data: 523977-64-2(Hazardous Substances Data)

Usage

Application

4-Bromo-2-cyanobenzaldehyde is a useful research chemical.

InChI:InChI=1S/C8H4BrNO/c9-8-2-1-6(5-11)7(3-8)4-10/h1-3,5H

Upstream product

• 529-19-1 2-Methylbenzonitrile 
• 156001-51-3 3-Bromo-6-methyl-benzonitrile 
• 50670-64-9 3-cyano-4-methylaniline 
• 939-83-3 2-cyano-4-nitrotoluene 
• 156001-53-5 5-bromo-2-(bromomethyl)benzonitrile 

Downstream Products

• 523977-68-6 C₁₆H₈Br₂N₂ 
• 1318689-68-7 4-(5-(p-(naphthylphenylamino)phenyl)-3,4-ethylenedioxythiophen-2-yl)-2-cyanobenzaldehyde 
• 867006-59-5 5-bromo-2-(morpholin-4-ylmethyl)benzonitrile 

Relevant articles and documents

Tetrazole derivative and preparation thereof, pharmaceutical composition containing tetrazole derivative and application of tetrazole derivative

The invention discloses a tetrazole derivative having a structure represented by a general formula I, wherein R1 is H, a C1-C3 alkyl chain or a halogenated alkyl chain. The invention also discloses acomposition containing the tetrazole derivative and an application of the tetrazole derivative in preparation of medicines for preventing and resisting cerebral apoplexy. Repeated experiments prove that the compound has an obvious inhibition effect on ADP-induced platelet aggregation activity, and has a good protection effect on OGD/R-damaged primary mouse nerve cell models and good rat oral medicine pharmacokinetic properties. Therefore, the compound disclosed by the invention can be used as a neuroprotective agent to be applied to medicines for treating and preventing cerebral apoplexy.

TETRAHYDRO-PYRIDO[3,4-b]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Synthesis and spectroscopic properties of finite Ph 2N-containing oligo(arylenevinylene) derivatives that emit blue to red fluorescence

(Matrix presented) A series of oligo(phenylenevinylene) (OPV) derivatives with finite conjugation units were prepared in short steps from few building blocks. The central and terminal aryl groups of these OPV dyes contain cyano and Ph2N substituents, respectively, which affect color of fluorescence. The wavelength ranges from 472 nm (blue) to 614 nm (red) depending on the position of the cyano group.