52398-48-8

Basic information

• Product Name: BETA,BETA-DIMETHYL-GAMMA-(HYDROXYMETHYL)-GAMMA-BUTYROLACTONE)
• Synonyms: BETA,BETA-DIMETHYL-GAMMA-(HYDROXYMETHYL)-GAMMA-BUTYROLACTONE);Tetrahydro-4,4-dimethyl-2H-pyran-2-one;(±)-5-Hydroxymethyl-4,4-dimethyldihydro-2(3H)-furanone;(±)-β,β-Dimethyl-γ-hydroxymethyl-γ-butyrolactone
• CAS NO: 52398-48-8
• Molecular Formula: C7H12O3
• Molecular Weight: 144.16838
• Mol File: 52398-48-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BETA,BETA-DIMETHYL-GAMMA-(HYDROXYMETHYL)-GAMMA-BUTYROLACTONE)(CAS DataBase Reference)
• NIST Chemistry Reference: BETA,BETA-DIMETHYL-GAMMA-(HYDROXYMETHYL)-GAMMA-BUTYROLACTONE)(52398-48-8)
• EPA Substance Registry System: BETA,BETA-DIMETHYL-GAMMA-(HYDROXYMETHYL)-GAMMA-BUTYROLACTONE)(52398-48-8)

Safety Data

• Hazardous Substances Data: 52398-48-8(Hazardous Substances Data)

Upstream product

• 77903-45-8 methyl 2,2-dimethyl-3-(trimethylsiloxy)-1-cyclopropanecarboxylate 

Relevant articles and documents

Ring Opening Reactions of Methyl 2-Siloxycyclopropanecarboxylates to Oxoalkanoic Acid Derivatives

A great variety of methyl 2-(trialkylsiloxy)cyclopropanecarboxylates C1 - C31 are cleaved under very mild conditions and with excellent yields providing 4-oxoalkanoic esters D1 - D31 which are important synthetic building blocks.Even sensible esters with formyl, vinyl ketone, or trimethylsiloxy functions can be prepared.Corresponding to the regioselective synthesis of C isomeric pairs of D can deliberately be constructed.In the presence of an electrophile alkylating ring opening delivers 4-oxoalkanoates substituted in position 2, however, the degree of alkylation does not exceed 60percent.Several other cleavage variations allow syntheses of other 4-oxoalkanoic acid derivatives in effective one-pot procedures.