523980-10-1

Upstream product

• 5544-60-5 4-(benzyloxy)benzyl bromide 
• 77278-84-3 tert-butyl 4-(4-(benzyloxy)benzyl)piperazine-1-carboxylate 

Downstream Products

• 1622426-35-0 (4-(4-(benzyloxy)benzyl)piperazin-1-yl)(1H-pyrazol-1-yl)methanone 
• 1622426-36-1 (4-(4-(benzyloxy)benzyl)piperazin-1-yl)(4-methyl-1H-pyrazol-1-yl)methanone 
• 1622426-37-2 1-(4-(4-(benzyloxy)benzyl)piperazine-1-carbonyl)-1H-pyrazole-4-carbonitrile 
• 1345843-89-1 ethyl 2-(4-(4-(benzyloxy)benzyl)piperazin-1-yl)acetate 
• 1345845-84-2 2-(4-(4-(benzyloxy)benzyl)piperazin-1-yl)-N'-(3,5-di-tert-butyl-2-hydroxybenzylidene)acetohydrazide 
• 1080005-83-9 2-(4-(4-(benzyloxy)benzyl)piperazin-1-yl)acetohydrazide 

Relevant academic research and scientific papers

Discovery libraries targeting the major enzyme classes: The serine hydrolases

Two libraries of modestly reactive ureas containing either electron-deficient acyl anilines or acyl pyrazoles were prepared and are reported as screening libraries for candidate serine hydrolase inhibitors. Within each library is a small but powerful subs

PROCASPASE-ACTIVATING COMPOUNDS AND COMPOSITIONS

The invention provides compounds and compositions useful for the modulation of certain enzymes. The compounds and compositions can induce of cell death, particularly cancer cell death. The invention also provides methods for the synthesis and use of the compounds and compositions, including the use of compounds and compositions in therapy for the treatment of cancer and selective induction of apoptosis in cells.