523980-99-6

Downstream Products

• 749913-57-3 1-(1,4-dioxa-spiro[4.5]dec-8-yl)-4-(2-iodo-benzyl)-piperazine 
• 1345843-77-7 2-(4-(2-iodobenzyl)piperazin-1-yl)acetohydrazide 
• 1345843-95-9 ethyl 2-(4-(2-iodobenzyl)piperazin-1-yl)acetate 
• 828934-55-0 2-hydroxy-5-[4-(2-iodo-benzyl)-piperazin-1-yl]-cyclohex-1-enecarboxylic acid benzo[1,3]dioxol-4-ylamide 
• 828934-81-2 2-hydroxy-5-[4-(2-iodo-benzyl)-piperazin-1-yl]-cyclohex-1-enecarboxylic acid (2,3-dimethoxy-phenyl)-amide 
• 749913-61-9 {4-[4-(2-iodo-benzyl)-piperazin-1-yl]-cyclohex-1-enyl}-dimethyl-amine 
• 749913-59-5 4-[4-(2-iodo-benzyl)-piperazin-1-yl]-cyclohexanone 

Relevant academic research and scientific papers

PROCASPASE-ACTIVATING COMPOUNDS AND COMPOSITIONS

The invention provides compounds and compositions useful for the modulation of certain enzymes. The compounds and compositions can induce of cell death, particularly cancer cell death. The invention also provides methods for the synthesis and use of the compounds and compositions, including the use of compounds and compositions in therapy for the treatment of cancer and selective induction of apoptosis in cells.

INHIBITORS OF STEAROYL-COA DESATURASE

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity.