52418-50-5

Basic information

• Product Name: 4,4-diMethyl-2-pentynoic acid
• Synonyms: 4,4-diMethyl-2-pentynoic acid
• CAS NO: 52418-50-5
• Molecular Formula: C₇H₁₀O₂
• Molecular Weight: 126.1531
• Mol File: 52418-50-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,4-diMethyl-2-pentynoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-diMethyl-2-pentynoic acid(52418-50-5)
• EPA Substance Registry System: 4,4-diMethyl-2-pentynoic acid(52418-50-5)

Safety Data

• Hazardous Substances Data: 52418-50-5(Hazardous Substances Data)

Usage

General Description

4,4-diMethyl-2-pentynoic acid, also known as DMPA, is a carboxylic acid compound with the chemical formula C7H10O2. It is a colorless liquid with a fruity odor that is commonly used as a building block in organic synthesis. DMPA is an important intermediate for the preparation of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a raw material for the production of plasticizers, UV stabilizers, and adhesives. DMPA has a wide range of industrial applications and is considered to be a versatile and valuable chemical compound.

Upstream product

• 83747-01-7 Diazo(1,2,3-tri-tert-butyl-2-cyclopropen-1-yl)essigsaeure-tert-butylester 
• 83747-03-9 2,3,4-Tri-tert-butylcyclobutadien-1-carbonsaeure-tert-butylester 

Downstream Products

• 66582-09-0 1-(3,3-dimethylbut-1-yn-1-yl)-4-methoxybenzene 
• 1448150-17-1 N-(1-(cyclohexylamino)-3-methyl-1-oxobutan-2-yl)-4,4-dimethyl-N-(prop-2-ynyl)pent-2-ynamide 
• 1448150-16-0 N-(2-(tert-butylamino)-1-(2-chloro-4-fluorophenyl)-2-oxoethyl)-4,4-dimethyl-N-(prop-2-yn-1-yl)pent-2-ynamide 
• 1448150-36-4 N-(tert-butyl)-2-(2-chloro-4-fluorophenyl)-2-(5,5-dimethyl-3-oxo-5,6-dihydro-1H-cyclopenta[c]pyridin-2(3H)-yl)acetamide 
• 1448150-15-9 N-(2-(tert-butylamino)-2-oxo-1-(2,3,4-trimethoxyphenyl)ethyl)-4,4-dimethyl-N-(prop-2-yn-1-yl)pent-2-ynamide 
• 1448150-35-3 N-(tert-butyl)-2-(5,5-dimethyl-3-oxo-5,6-dihydro-1H-cyclopenta[c]pyridin-2(3H)-yl)-2-(2,3,4-trimethoxyphenyl)acetamide 
• 1448150-14-8 N-(2-(tert-butylamino)-1-(4-methoxyphenyl)-2-oxoethyl)-4,4-dimethyl-N-(prop-2-ynyl)pent-2-ynamide 
• 1448150-34-2 N-(tert-butyl)-2-(5,5-dimethyl-3-oxo-5,6-dihydro-1H-cyclopenta[c]pyridin-2(3H)-yl)-2-(4-methoxyphenyl)acetamide 
• 1448150-26-2 N-(2-(butylamino)-2-oxo-1-p-tolylethyl)-4,4-dimethyl-N-(prop-2-ynyl)pent-2-ynamide 
• 1448150-46-6 N-butyl-2-(5,6-dihydro-5,5-dimethyl-3-oxo-1H-cyclopenta[c]pyridin-2(3H)-yl)-2-p-tolylacetamide 
• 1448150-28-4 N-(2-(cyclohexylamino)-2-oxo-1-(p-tolyl)ethyl)-4,4-dimethyl-N-(2-methylbut-3-yn-2-yl)pent-2-ynamide 
• 1448150-18-2 N-(2-(cyclohexylamino)-2-oxo-1-p-tolylethyl)-4,4-dimethyl-N-(prop-2-ynyl)pent-2-ynamide 
• 1448150-38-6 N-cyclohexyl-2-(5,5-dimethyl-3-oxo-5,6-dihydro-1H-cyclopenta[c]pyridin-2(3H)-yl)-2-(p-tolyl)acetamide 

Relevant articles and documents

Carbenes, 28. tert-Butyl 2,3,4-Tri-tert-butylcyclobutadiene-1-carboxylate

The cyclopropenyldiazoacetate 3a - available from tri-tert-butylcyclopropenylium bromide (1) and the mercury bis(diazoacetate) 2a - is the starting material for the synthesis of the title compound 5a.The carbene 4a, generated photolytically from 3a, is responsible for the formation of both the cyclobutadiene 5a and the acetylenes 6 and 7a.Acetylene formation is also observed in the flash pyrolysis of 3a (formation of 6, 7a, 8, and 9) and 5a (formation of 6, 8, and 9).The extremely air sensitive cyclobutadiene 5a ( -> 16) shows a pronounced cycloaddition behaviour towards dienophiles.With dimethyl ac etylenedicarboxylate, maleic anhydride, cyclopentadiene, diethyl azodicarboxylate and 4-phenyl-1,2,4-triazoline-3,5-dione cycloadducts were isolated (17, 18, 19, 20, 21).The series of the diazadihydro Dewar benzenes is also entered by the reaction of the cyclopropenyldiazoacetates 3 with the triazolinedione; the betaines 22 and 24 are regarded to be intermediates of this reaction.