Prednisolone is a synthetic glucocorticoid and a corticosteroid medication that possesses potent anti-inflammatory and immunosuppressive properties. It is derived from hydrocortisone and is used to treat a wide range of conditions by reducing inflammation and suppressing the immune system. This helps to alleviate symptoms such as swelling, redness, itching, and allergic reactions, making it a versatile pharmaceutical agent for various applications.
52438-85-4
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Basic information
- Product Name: PREDNISOLONE
- Synonyms: METACORT AND RALONE;METACORTANDROLONE;DEHYDROHYDROCORTISONE;HYDRODELTALONE;(8S,9S,10R,11S,13S,14S,17R)-11,17-DIHYDROXY-17-(2-HYDROXY-ACETYL)-10,13-DIMETHYL-6,7,8,9,10,11,12,13,14,15,16,17-DODECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE;11BETA 17,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE;11-BETA,17-ALPHA,21-HYDROXY-1,4-PREGNADIENE-3,20-DIONE;11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE
- CAS NO:52438-85-4
- Molecular Formula: C21H28O5
- Molecular Weight: 360.44
- EINECS: 200-021-7
- Product Categories: Steroids
- Mol File: 52438-85-4.mol
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Chemical Properties
- Melting Point: 240 °C (dec.)(lit.)
- Boiling Point: 570.6 °C at 760 mmHg
- Flash Point: 313 °C
- Appearance: /
- Density: 1.31 g/cm3
- Vapor Pressure: 7.36E-16mmHg at 25°C
- Refractive Index: 1.587
- Storage Temp.: 0-6°C
- Solubility: N/A
- CAS DataBase Reference: PREDNISOLONE(CAS DataBase Reference)
- NIST Chemistry Reference: PREDNISOLONE(52438-85-4)
- EPA Substance Registry System: PREDNISOLONE(52438-85-4)
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Safety Data
- Hazard Codes: Xn
- Statements: 22
- Safety Statements: N/A
- WGK Germany: 3
- RTECS: TU4152000
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 52438-85-4(Hazardous Substances Data)
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52438-85-4 Usage
Uses
Used in Medical Applications:Prednisolone is used as an anti-inflammatory and immunosuppressive agent for treating various conditions, including inflammation, allergies, and autoimmune disorders. It is effective in reducing inflammation and suppressing the immune system, which helps to alleviate symptoms such as swelling, redness, itching, and allergic reactions.
Used in Oncology:
Prednisolone is used as a therapeutic agent for treating certain types of cancer. Its anti-inflammatory and immunosuppressive properties can help manage cancer-related symptoms and improve the patient's quality of life.
Used in Dermatology:
Prednisolone is used as a topical treatment for various skin conditions, such as eczema, psoriasis, and dermatitis. Its anti-inflammatory properties help to reduce skin inflammation, itching, and redness, providing relief to patients suffering from these conditions.
Used in Respiratory Disorders:
Prednisolone is used as a treatment for respiratory disorders, such as asthma and chronic obstructive pulmonary disease (COPD). It helps to reduce inflammation in the airways, improving lung function and reducing symptoms associated with these conditions.
Prednisolone is available in several forms, including tablets, oral liquid, and injections, allowing for flexible administration based on the specific needs of the patient. However, it is essential to use Prednisolone under the guidance of a healthcare professional due to potential side effects and interactions with other medications.
Check Digit Verification of cas no
The CAS Registry Mumber 52438-85-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,3 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.Calculate Digit Verification of CAS Registry Number 52438-85:
(7*5)+(6*2)+(5*4)+(4*3)+(3*8)+(2*8)+(1*5)=124
124 % 10 = 4
So 52438-85-4 is a valid CAS Registry Number.
InChI:InChI=1/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h6,8,10,16-18,20,26,28H,4-5,7,9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
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