5244-34-8Relevant articles and documents
Binuclear and mononuclear Cu(II) and Ni(II) complexes of tetra- and hexadentate ligands: Synthesis, antifungal activity, spectroscopic and thermal characterization
Turkyilmaz, Murat
, p. 451 - 460 (2017)
Two tetradentate ligands, 1,2-bis(2-hydroxyethylthio)ethane S2O2 (L1) and N,N′-bis(2-hydoxypropyl)piperazine N2O2 (L2), were prepared by organization of some mononuclear complexes of Cu(II) and Ni(II). A new binuclear Schiff base ligand with a 1,4-dipropoxybutane spacer provided by the reaction of salicylaldehyde and 1,4-bis(3-aminopropoxy)butane served as an octadentate, N2O4 (L3) ligand, in designing some binuclear complexes with metal ions. All the ligands were characterized by elemental analyses, FTIR, 1H and 13C NMR and GC–MS. The complexes were characterized by elemental analyses, FTIR, thermal methods, electronic spectra, conductivity and magnetic measurements. The metal ions coordinate to the ligands with four donor atoms in square planar geometry. The thermal stabilities of the complexes were discussed in terms of metal ions and type of donor atoms. The complexes were characterized by electronic spectra and magnetic susceptibility measurements to establish the proposed four-coordinated square planar geometry. The TG chart indicates high thermal stability for complexes. The decomposition processes consisted of three stages: The first two stages involve the loss of water and chloride anions and the last stage indicates degradation of the organic ligands. The antifungal activity of the ligands and their complexes was tested against several fungal species: Aspergillus nigar, Aspergillus flavus and Candida albicans. The results show that complexes have significant antifungal activities compared to their parent ligands.
Unexpected Reaction Pathways Leading to Thiodiglycol during the Degradation of Long-Chain Sulfur Mustards
Gómez-Caballero, Esther,Martínez-álvarez, Roberto,Sierra, Miguel A.
, p. 12432 - 12439 (2018/10/15)
Degradation of long-chain sulfur mustards with various commercial decontaminants unexpectedly forms thiodiglycol (TDG) through unreported reaction pathways. Chemical warfare agents (CWAs) degradation products have to be unambiguously related to their reference compounds in order to fulfill international verification protocols. Thus, the formation of TDG using water-based decontaminants introduces an uncertainty in the origin of this chemical that has been systematically used to unambiguously demonstrate the presence of yperite in environmental and biomedical samples. Therefore, these novel and unprecedented degradation pathways will result either in modifications of the international verification protocols for forensic purposes or in the exclusion of TDG as an exclusive marker of yperite.
Synthesis and biological evaluation of some new thioether-ester crown ethers
Seyedi, Seyed Mohammad,Sadeghian, Ali,Sadeghian, Hamid,Hazrathoseyni, Ayla,Sadeghian, Mohammad
, p. 265 - 272 (2007/10/03)
New thioether-ester crown ethers have been synthesized starting from oxalyl chloride and different β,β′-dihydroxydithioethers. The synthesized compounds are screened for their antibacterial activity. Among the macrocyclic thioether-esters (5a-j), only 5,12-di[(allyloxy)methyl]-1,4-dioxa-7, 10-dithiacyclododecane-2,3-dione (5e) and 5,12-di(isopropoxymethyl)-1,4-dioxa-7, 10-dithiacyclododecane-2,3-dione (5f) were effective inhibitors against Staphilococcus aureus methicillin resistance and Pseudomanas aeruginosa with an MIC value of 525 and 265 μM. Structures of the synthesized compounds have been confirmed by 1H NMR, 13C NMR, and MS spectral studies. Copyright Taylor & Francis Group, LLC.
