52443-16-0Relevant articles and documents
Synthesis of pyrrolo[2,3-d]pyrimidine nucleoside derivatives as potential anti-HCV agents
Varaprasad, Chamakura V.N.S.,Ramasamy, Kanda S.,Girardet, Jean-Luc,Gunic, Esmir,Lai, Vicky,Zhong, Weidong,An, Haoyun,Hong, Zhi
, p. 25 - 34 (2008/02/11)
Several Toyocamycin (4) analogues were examined for their ability to inhibit HCV RNA in a replicon assay. Among the compounds examined 4-methylthio (18) and 5-carboxamide oxime derivatives (23 and 27) of Toyocamycin were found to have good activity and selectivity.