52448-84-7Relevant academic research and scientific papers
Aerobic thiyl radical addition/cyclization of N-methacryloyl benzamides for the synthesis of isoquinoline-1,3(2H,4H)-dione derivatives
Yuan, Yan-Qin,Kumar, Pailla Santhosh,Zhang, Chun-Niu,Yang, Ming-Hua,Guo, Sheng-Rong
, p. 7330 - 7338 (2017)
A highly effective oxidative thiyl radical addition/cyclization of N-methacryloylbenzamides was explored using dioxygen as the sole terminal oxidant without the use of precious and/or toxic transition-metal catalysts. This method provides convenient access to a variety of useful sulfide-containing 4,4-disubstituted isoquinoline-1,3-diones by constructing C-S and C-C bonds in one step.
