52476-79-6 Usage
Chemical Class
Tetrazolo-phthalazine derivative
Structure
Heterocyclic compound
Contains a tetrazole ring and a phthalazine ring
An ethoxy group attached to the aromatic ring
Biological and Pharmacological Activities
Potential antihypertensive properties
Potential antiarrhythmic properties
Potential antidyslipidemic properties
Applications
Pharmaceuticals: Potential for treating cardiovascular diseases
Materials Science: Possible use in the development of organic light-emitting diodes (OLEDs) and other electronic devices
Research Status
Further research is needed to fully understand its potential uses and effects.
Check Digit Verification of cas no
The CAS Registry Mumber 52476-79-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,7 and 6 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 52476-79:
(7*5)+(6*2)+(5*4)+(4*7)+(3*6)+(2*7)+(1*9)=136
136 % 10 = 6
So 52476-79-6 is a valid CAS Registry Number.
52476-79-6Relevant academic research and scientific papers
Synthesis and primary anticonvulsant activity evaluation of 6-alkyoxyl-tetrazolo[5,1-a]phthalazine derivatives
Sun, Xian-Yu,Wei, Cheng-Xi,Deng, Xian-Qing,Sun, Zhi-Gang,Quan, Zhe-Shan
, p. 289 - 292 (2011/09/20)
A new series of 6-alkyoxyl-tetrazolo[5,1-a] phthalazine derivatives (4 a-4 o) were synthesized as potential anticonvulsant agents. Anticonvulsant activity was evaluated by the maximal electroshock (MES) test. Neurotoxicity was evaluated by the rotarod neurotoxicity test. The pharmacological results showed that 6-(4-chlorophenyoxyl)-tetrazolo[5,1-a]phthalazine (4 m) was the most potent agent, with a median effective dose (ED50) of 6.8 mg/kg and a median neurotoxic dose (TD50) of 456.4 mg/kg. The protective index (PI = TD50/ED50) for compound 4m was 67.1, which was significantly higher than that for the reference drug carbamazepine (PI = 6.4). ECV Editio Cantor Verlag.
