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8-methoxy-9-methyl-2-(propan-2-yl)-3,9-dihydrofuro[2,3-b]quinolin-4(2H)-one is a complex organic compound belonging to the class of furanochromenone derivatives. This molecule features a furan ring fused to a quinolinone core, with a methyl group at the 9-position, a methoxy group at the 8-position, and a propyl group attached to the 2-position. The compound is characterized by its unique structure, which may exhibit various biological activities and potential applications in pharmaceuticals or chemical research. Its chemical properties and reactivity can be influenced by the presence of these functional groups, making it an interesting subject for further investigation in the field of organic chemistry.

52486-77-8

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52486-77-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 52486-77-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,8 and 6 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 52486-77:
(7*5)+(6*2)+(5*4)+(4*8)+(3*6)+(2*7)+(1*7)=138
138 % 10 = 8
So 52486-77-8 is a valid CAS Registry Number.

52486-77-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-methoxy-9-methyl-2-propan-2-yl-2,3-dihydrofuro[2,3-b]quinolin-4-one

1.2 Other means of identification

Product number -
Other names LUNACRINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52486-77-8 SDS

52486-77-8Relevant academic research and scientific papers

Quinoline alkaloids: Synthesis of pyrano[2,3,-b]quinolines, khaplofoline, lunacrine, and demethoxylunacrine

Sekar,Prasad

, p. 294 - 296 (2007/10/03)

Polyphosphoric acid (PPA)-catalyzed cyclization of 2-ono-3- vinylquinolinecarboxylic acid (1) yielded 3,4-dihydro-2,2-dimethyl-2H- pyrano[2,3-b]quinoline (4). The same reaction of 4-methoxy-2-oxo-3- vinylquinolinecarboxylic acid (1g) afforded 4-methoxy-2,2-dimethylpyrano[2,3- b]-quinoline (4g), which on hydrolysis with ethanolic hydrochloric acid gave khaplofoline (5). The Prevost reaction of 4-methoxy-3-prenylquinolin-2-one (6) using I2/HgO in acetic acid yielded 4-methoxy-2-isopropylfuro[2,3- b]quinoline (7). Compound 7 on reduction with H2/Pd-C followed by N- methylation and de-O-methylation afforded lunacrine (10a). A similar reaction sequence on 6b gave demethoxylunacrine (10b).

SYNTHESIS OF 2-ISOPROPYLFURO(2,3-b)QUINOLINES-A NEW SYNTHESIS OF (+/-)-LUNACRINE, (+/-)-LUNASINE AND (+/-)-DEMETHOXYLUNACRINE

Ramesh, M.,Mohan, P.S.,Shanmugam, P.

, p. 3431 - 3436 (2007/10/02)

A new and convenient synthesis of 2-isopropylfuro(2,3-b)quinolines (4) from 3-(3-methylbut-1-enyl)-2-quinolones (2) is described.A neat synthesis of the alkaloids (+/-)-lunacrine (1a), (+/-)-lunasine (12a) and (+/-)-demethoxylunacrine (1b) is also reported.

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