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Upstream product

• 20379-61-7 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl azide 
• 13992-25-1 1-azido-1-deoxy-β-D-glucopyranoside tetraacetate 
• 98300-76-6 2,3,4,6-tetra-O-acetylglucopyranosyl 1-amine 
• 1885-14-9 phenyl chloroformate 
• 41355-50-4 2,3,4,6-tetra-O-acetyl-D-glucosyl-1-amine 

Relevant academic research and scientific papers

Further development of the tin-catalyzed transcarbamoylation reaction

Studies carried out to further develop tin-catalyzed trans-carbamoylation reactions demonstrated that transcarbamoylation of cinnamyl alcohol in the context of allyl cyanate-to-isocyanate rearrangement can be efficiently carried out on a ten-gram scale and that tin-catalyzed transcarbamoylation is a valuable alternative to the method using trichloroacetyl isocyanate. In addition, methyl carbamate was found to be an economical carabamoyl donor in tin-catalyzed transcarbamoylation, which showed broad functional group tolerance and allowed a streamlined workup procedure. Finally, a unique synthetic method was developed for the preparation of carbamate-tethered terpene glycoconjugates.

Stereospecific synthesis of urea-tethered neoglycoconjugates starting from glucopyranosyl carbamates

Silyl-assisted elimination reaction of glucopyranosyl carbamates has been established for the synthesis of α- and β-D-glucopyranosyl isocyanates and ureas. This method proved to be useful for the synthesis of urea-tethered neoglycoconjugates.

Glucopyranosyl isocyanates as versatile glycosylating reagents for the preparation of neoglycoconjugates

A new and simple synthetic method for the preparation of glucopyranosyl isocyanates has been developed. This method establishes a convenient access to the urea- and carbamate-tethered neoglycoconjugates starting from glucopyranosyl isocyanates.