52498-53-0Relevant articles and documents
Mesoionic Carbene-Iridium Complex Catalyzed Ortho-Selective Hydrogen Isotope Exchange of Anilines with High Functional Group Tolerance
Cao, Lei,Huang, Linwei,Huang, Shiqing,Liu, Wei,Yan, Xiaoyu,Zhang, Gang,Zhang, Zengyu,Zhao, Peng
, (2020)
Mesoionic carbene-iridium complex 1a has been investigated in the hydrogen isotope exchange (HIE) reaction of anilines. By employing 1 mol % of 1a as catalyst, anilines were selectively deuterated at the ortho-position with high deuteration levels. High ortho-selectivity was observed for anilines with various competing directing groups, which is in contrast with catalytic results of Kerr's catalysts.